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TranscriptomicsGene exrpression profiling of childhood adrenocortical tumors
Pediatric adrenocortical tumors (ACT) are rare and often fatal malignancies; little is known regarding their etiology and biology. To provide additional insight into the nature of ACT, we determined the gene expression profiles of 24 pediatric tumors (five adenomas, 18 carcinomas, and one undetermin...
ORGANISM(S): Homo sapiens 
2015-11-25 | E-GEOD-75415 | biostudies-arrayexpress
ProteomicsProteomic Profile of Human Benign and Malignant Adrenocortical Neoplasia.
The molecular pathogenesis of adrenocortical diseases, particularly adrenocortical carcinoma (ACC), has advanced considerably in recent years due to the application of high-throughput molecular analysis. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) offers an approach for identifying and...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD062822 | Pride
Human adrenal gland Adrenocortical tumors Adrenocortical carcinoma Normal adrenal cortex Adrenocortical adenona Primary macronodular adrenocortical hyperplasia 
TranscriptomicsAnalysis of circulating microRNAs in adrenocortical tumours
Differential diagnosis of adrenocortical adenoma and carcinoma is of pivotal clinical relevance, as the prognosis and clinical management of benign and malignant adrenocortical tumours is entirely different. Circulating microRNAs are promising biomarker candidates of malignancy in several tumours. I...
ORGANISM(S): Homo sapiens 
2013-11-19 | E-GEOD-49674 | biostudies-arrayexpress
GenomicsmicroRNa expression profiling in adrenal myelolipoma, adrenocortical carcinoma and adrenocortical adenoma
microRNa expression profiling in adrenal myelolipoma, adrenocortical carcinoma and adrenocortical adenoma
PRJNA449060 | ENA
Proteomicsproteomics of pediatric adrenocortical tumors
Pediatric adrenocortical tumors (pACT) are biologically heterogeneous and incompletely classified by histopathology. To elucidate proteome-level tumor organization, we performed mass spectrometry–based proteomic profiling of 83 pACT and 43 normal adrenal samples. Unsupervised clustering identified f...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD080313 | Pride
Adrenocortical tumors Adrenocortical carcinoma Adrenocortical adenoma Pediatric cancer 
TranscriptomicsTranscription profiling of human adrenocortical carcinomas (33), adenomas (22), and normal adrenal cortex (10)
Human samples of 33 adrenocortical carcinomas, 22 adrenocortical adenomas, and 10 normal adrenal cortex samples, each from a different patient, had mRNA assays performed using Affymetrix HG_U133_plus_2 arrays, with 54675 probe-sets. Experiment Overall Design: Two supplementary files are attached bel...
ORGANISM(S): Homo sapiens 
2009-02-07 | E-GEOD-10927 | biostudies-arrayexpress
TranscriptomicsHuman Adrenocortical Tumors: normal cortex vs inactive adenoma vs cortisol secreting adenoma vs adrenocortical cancer
Transcriptional profiling of human adrenocortical tumors. Gene expression profile of normal adrenal cortex, hormonally inactive adenoma, cortisol-secreting Cushing-adenoma and primary adrenocortical cancer tissues were compared. The goal of this study was to identify significant differences in the g...
ORGANISM(S): Homo sapiens 
2009-07-01 | GSE14922 | GEO
TranscriptomicsTranscription profiling by array of human adrenocortical tumors to identify molecular predictors of diagnosis and prognosis
A ""Cartes d'Identite des Tumeurs"" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). 92 samples on Affymetrix HG-U133 Plus 2.0 GeneChips arrays for 92 patients with Adrenocortical Tumors (ACT). 4 normal adrenal samples from the same batch are also include...
ORGANISM(S): Homo sapiens 
2009-01-15 | E-TABM-311 | biostudies-arrayexpress
TranscriptomicsSteroids-producing adrenocortical nodules (bulk RNA-seq)
This data was used in the analysis of the article titled ‘Steroids-producing adrenocortical nodules: a novel two-layered structure as a precursor lesion of cortisol-producing adenoma’.
ORGANISM(S): Homo sapiens 
2023-07-20 | E-MTAB-13109 | biostudies-arrayexpress
TranscriptomicsExpression data from normal adrenal gland and aldosterone-producing adenoma
The source of aldosterone in 30 to 40 % of patients with primary hyperaldosteronism (PA) is unilateral aldosterone-producing adenoma (APA). The mechanisms causing elevated aldosterone production in APA are unknown. Herein, we examined expression of G-protein coupled receptors (GPCR) in APA and demon...
ORGANISM(S): Homo sapiens 
2007-07-18 | E-GEOD-8514 | biostudies-arrayexpress
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