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GenomicsGenome-wide DNA methylation profiles of non-small cell lung carcinomas and control lung tissues
Purpose: Generate genome-wide methylation profiles of non-small cell lung carcinomas (NSCLC) and their matching lung tissues for detection of hypermethylated and hypomethylated regions present in the tumors. Methods: MethylCapture followed by next-generation sequencing (Illumina GAIIx) of 7 nsclc tu...
ORGANISM(S): Homo sapiens 
2012-10-05 | E-GEOD-41343 | biostudies-arrayexpress
Genomicsena-DATASET-RTL-03-05-2017-12:40:06:735-476 - samples
RNAseq of LC2AD with AD80 or DMSO Plenker et al., Mechanistic insight into RET kinase inhibitors targeting the DFG-out conformation in RET-rearranged cancer
EGAD00001003316 | EGA
GenomicsDrugging the catalytically inactive state of RET kinase in RET-rearranged tumors.
Oncogenic fusion events have been identified in a broad range of tumors. Among them, RET rearrangements represent distinct and potentially druggable targets that are recurrently found in lung adenocarcinomas. We provide further evidence that current anti-RET drugs may not be potent enough to induce ...
EGAS00001002335 | EGA
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