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ProteomicsProteomic Analysis on Anti-proliferative and Apoptosis Effects of Curcumin Analogue, 1,5-bis(4-hydroxy-3-methyoxyphenyl)-1,4-pentadiene-3-one Treated Human Glioblastoma and Neuroblastoma Cells
A label free shotgun proteomic analysis that defined the protein profiles in neuroblastoma cells.
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024565 | Pride
Human Glioblastoma Agilent 6550 ifunnel q-tof 
ProteomicsLC-MS/MS data for metabolite production by Streptomyces baldaccii NRRL B-3500 in monoculture and grasshopper-associated conditions
LC-MS/MS data of metabolites produced by Streptomyces baldaccii NRRL B-3500 grown in monoculture (ISP2, A-medium, and RAM2) and grasshopper-associated conditions. The dataset includes monoculture extracts, grasshopper-associated samples (+GH), grasshopper controls without bacteria (BLK+GH), and met...
ORGANISM(S): Streptomyces Baldaccii Nrrl B-3500 
2026-02-25 | MSV000100974 | MassIVE
MetabolomicsIn-depth characterization of the CaV2.2-knockout mouse line

ABSTRACT The voltage-gated calcium channel CaV2.2 is predominantly located in neuronal synapses, where it plays a role in pain signaling and neurotransmitter release. Furthermore, CaV2.2 is important during early central nervous system development, as it is subsequently replaced by other calcium ...

2026-07-09 | MTBLS14319 | MetaboLights
MetabolomicsNeuroactive Potential Signatures of the Gut Microbiome Across Prokaryotic Genomes and Neuropsychiatric Conditions Using GBM2

Neuropsychiatric conditions impose a substantial global burden, yet the contribution of microbiota–gut–brain communication to their biology remains difficult to interpret in humans. Metagenomic studies could help characterize microbial neuroactive potential, but such analyses remain constrained b...

2026-08-07 | MTBLS7381 | MetaboLights
MetabolomicsMicrobial metabolites calibrate innate immunity upon systemic viral infection

Gut microbiome dysbiosis is often associated with immune-mediated diseases. Here, we used germ-free (GF) mice, the synthetic minimal consortium OMM12, and specific pathogen-free (SPF) mice to dissect the causal influence of the microbiome on anti-viral immunity. The lack of microbial diversity af...

2026-08-01 | MTBLS7382 | MetaboLights
MetabolomicsClay vs Glass: Root exudate recovery from two distinct microcosm systems

Plant roots host defined microbial communities that differ from those in the surrounding soil, and these communities shift dynamically in response to plant development and environmental changes. Whilst it is widely accepted that root exudates play a key role in the assembly and dynamics of root-a...

2026-09-16 | MTBLS14524 | MetaboLights
MetabolomicsIdentification of metabolites of trifunctional sphingomyelin (TFSM1) in HeLa 229 cells infected with Chlamydia trachomatis

Chlamydia trachomatis is an obligate intracellular bacterial pathogen and a leading cause of sexually transmitted infections worldwide. During its biphasic developmental cycle, infectious, non-replicative elementary bodies alternate with replicative reticulate bodies within a membrane-bound intra...

2026-08-10 | MTBLS15303 | MetaboLights
MetabolomicsGlass vs Clay: dynamic responses of the root exudate, root and shoot tissue metabolome upon SynCom colonisation

Plant roots host defined microbial communities that differ from those in the surrounding soil, and these communities shift dynamically in response to plant development and environmental changes. Whilst it is widely accepted that root exudates play a key role in the assembly and dynamics of root-a...

2026-09-16 | MTBLS14526 | MetaboLights
MetabolomicsMetabolomics of Solanum lycopersicum infected by Phytophthora infestans leads to Late blight detection and reveals metabolic differences in infection times
Tomato crops suffer attacks of various pathogens that cause large production losses. Late blight caused by Phytophthora infestans is a devastating disease in tomatoes because of its difficultly to control. Here, we applied metabolomics based on liquid chromatography–mass spectrometry (LC-MS) and met...
2019-01-24 | MTBLS618 | MetaboLights
MetabolomicsFlow cytometry has a significant impact on the cellular metabolome (General LC-MS assay)
The characterization of specialized cell subpopulations in a heterogeneous tissue is essential for understanding organ function in health and disease. A popular method of cell isolation is fluorescence-activated cell sorting (FACS) based on probes that bind surface or intracellular markers. In this ...
2018-11-06 | MTBLS629 | MetaboLights
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