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UnknownAccumulation of SA-βGal-High Cells in Human Naive T Cell Compartments Reveals a Stress-Adapted, Senescent-Like State.
Aging is associated with a decline in immune function termed immunosenescence, characterized by accumulation of senescent-like immune cells and chronic inflammation, known as inflammaging. While senescence-associated β-galactosidase (SA-βGal) activity is a well-established senescence marker, its fun...
S-EPMC12259081 | biostudies-literature
UnknownIncreased default mode network activation in depression and social anxiety during upward social comparison.
Social comparisons are a core feature of human life. Theories posit that social comparisons play a critical role in depression and social anxiety triggering negative evaluations about the self, as well as negative emotions. We investigated the neural basis of social comparisons in participants with ...
S-EPMC11792650 | biostudies-literature
UnknownExcess tuberculosis risk during and following incarceration in Paraguay: a retrospective cohort study.

Background

The increased risk of tuberculosis (TB) among people deprived of liberty (PDL) is due to individual and institution-level factors. We followed a cohort of PDL from 5 prisons in Paraguay to describe the risk of TB during incarceration and after they were released.

Methods

We...
S-EPMC10945421 | biostudies-literature
UnknownFast raster-scan optoacoustic mesoscopy enables assessment of human melanoma microvasculature in vivo.
Melanoma is associated with angiogenesis and vascular changes that may extend through the entire skin depth. Three-dimensional imaging of vascular characteristics in skin lesions could therefore allow diagnostic insights not available by conventional visual inspection. Raster-scan optoacoustic mesos...
S-EPMC9120110 | biostudies-literature
UnknownMetagenome-assembled bacterial genomes recovered from the datasets of Spodoptera frugiperda (Smith) (Lepidoptera: Noctuidae).
Spodoptera frugiperda (Smith) (Lepidoptera: Noctuidae), also known as the fall armyworm, is an economically important and widespread polyphagous pest. Microorganisms associated to this insect during life cycle play important ecological roles. We report 3 metagenome-assembled bacterial genomes...
S-EPMC10788226 | biostudies-literature
ProteomicsCancer-restricted cryptic antigens are targets for T cell recognition
Ely ZA, Kulstad ZJ, Gunaydin G, Addepalli S, Verzani EK, Casarrubios M, Clauser KR, Wang X, Lippincott IE, Louvet C, Schmitt T, Kapner KS, Agus MP, Hennessey CJ, Cleary JM, Hadrup SR, Klaeger S, Su J, Jaeger AM, Wolpin BM, Raghavan S, Smith EL, Greenberg PD, Aguirre AJ, Abelin JG, Carr SA, Jacks T, ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-01-15 | MSV000096853 | MassIVE
UnknownMycobiota of Mexican Maize Landraces with Auxin-Producing Yeasts That Improve Plant Growth and Root Development.
Compared to agrochemicals, bioinoculants based on plant microbiomes are a sustainable option for increasing crop yields and soil fertility. From the Mexican maize landrace "Raza cónico" (red and blue varieties), we identified yeasts and evaluated in vitro their ability to promote plant growth. Auxin...
S-EPMC10058334 | biostudies-literature
TranscriptomicsReal-time quantitative PCR analysis of mouse lungs
Balb/cJ mouse received control RNAi or RNAi to 8-oxoguanine DNA glycosylase (Ogg1) intranasally prior to the exposure for 1 h to a) glucose oxidase (1 mU) to induce OGG1-BER or b) OGG1-BER product 8-oxoguanine (1 M-NM-
ORGANISM(S): Mus musculus 
2014-08-26 | E-GEOD-60711 | biostudies-arrayexpress
UnknownNext generation yellow fever vaccine induces an equivalent immune and transcriptomic profile to the current vaccine: observations from a phase I randomised clinical trial.

Background

Yellow fever (YF), a mosquito-borne acute viral haemorrhagic illness, is endemic to many tropical and subtropical areas of Africa and Central and South America. Vaccination remains the most effective prevention strategy; however, as repeated outbreaks have exhausted vaccine stockp...
S-EPMC11424963 | biostudies-literature
UnknownThe genetic history of Portugal over the past 5,000 years.

Background

Recent ancient DNA studies uncovering large-scale demographic events in Iberia have presented very limited data for Portugal, a country located at the westernmost edge of continental Eurasia. Here, we present the most comprehensive collection of Portuguese ancient genome-wide data...
S-EPMC12360031 | biostudies-literature
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