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TranscriptomicsThe immunomodulatory effects of IL-4 on monocyte-derived macrophages
To explore the effects of IL-4 on tumor-associated macrophagess, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. We then stimulate...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-75829 | biostudies-arrayexpress
TranscriptomicsHuman cathelicidin antimicrobial peptide LL37 effect on human neonatal epidermal keratinocytes (NHEKs).
Analysis of undifferentiated keratinocytes or differentiated keratinocytes stimulated with or without human cathelicidin antimicrobial peptide (CAMP) LL37. Results provide insight into the biological effects of CAMP on human keratinocytes. NHEKs were divided into two groups; low calcium (0.05 mM) an...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-49472 | biostudies-arrayexpress
TranscriptomicsThe immunomodulatory effects of soluble receptor of activated nuclear factor kappa ligand (sRANKL) on monocyte-derived macrophages
To explore the effects of sRANKL on tumor-associated macrophages, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. We then stimulat...
ORGANISM(S): Homo sapiens 
2015-08-24 | E-GEOD-72292 | biostudies-arrayexpress
TranscriptomicsThe immunomodulatory effects of periostin on monocyte-derived macrophages
To explore the effects of periostin on tumor-associated macrophagess, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. In the absen...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-70821 | biostudies-arrayexpress
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