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TranscriptomicsNickel Chloride (NiCl2) effect on human T cells from whole blood
Analysis of anti-CD3/anti-CD28 stimulated T cells treated with or without nickel chloride. Nickel is the most important contact allergen in the general population of the industrialized world. Results provide insight into the biological effects of nickel on human CD3+ T cells. We obtained mRNA of pur...
ORGANISM(S): Homo sapiens 
2011-05-18 | E-GEOD-23387 | biostudies-arrayexpress
TranscriptomicsThe immunomodulatory effects of IL-4 on monocyte-derived macrophages
To explore the effects of IL-4 on tumor-associated macrophagess, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. We then stimulate...
ORGANISM(S): Homo sapiens 
2015-12-10 | E-GEOD-75829 | biostudies-arrayexpress
TranscriptomicsInterleukin-4 and interleukin-13 cytokines effect on epidermal keratinocytes
Analysis of cultured epidermal keratinocytes treated with interleukin-4 (IL-4) and interleukin-13 (IL-13). IL-4 and IL-13 are up-regulated in atopic dermatitis. Results provide insight into the role of IL-4 and IL-13 cytokines in the pathogenesis of atopic dermatitis. Analysis of epidermal keratino...
ORGANISM(S): Homo sapiens 
2010-10-31 | E-GEOD-20706 | biostudies-arrayexpress
TranscriptomicsThe immunomodulatory effects of periostin on monocyte-derived macrophages
To explore the effects of periostin on tumor-associated macrophagess, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. In the absen...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-70821 | biostudies-arrayexpress
TranscriptomicsThe immunomodulatory effects of soluble receptor of activated nuclear factor kappa ligand (sRANKL) on monocyte-derived macrophages
To explore the effects of sRANKL on tumor-associated macrophages, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. We then stimulat...
ORGANISM(S): Homo sapiens 
2015-08-24 | E-GEOD-72292 | biostudies-arrayexpress
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