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Inhibition or genetic deletion of poly(ADP-ribose) polymerase-1 (PARP-1) is profoundly protective against a number of toxic insults in many organ systems1,2. In the brain the molecular mechanisms underlying PARP-1-dependent cell death (parthanatos) involves mitochondrial apoptosis-inducing factor (A...
ORGANISM(S): Homo sapiens 
2016-12-19 | GSE65110 | GEO
Transcriptional profiling of muscle and liver samples from muscle- and liver-specific AIF knockout mice respectively. Samples obtained from 8 week old, male knockouts, backcrossed 8 times onto the C57Bl6 background are compared to those obtained from littermate control mice. Keywords: disease state ...
ORGANISM(S): Mus musculus 
2007-08-29 | GSE8904 | GEO
Transcriptional profiling of muscle and liver samples from muscle- and liver-specific AIF knockout mice respectively. Samples obtained from 8 week old, male knockouts, backcrossed 8 times onto the C57Bl6 background are compared to those obtained from littermate control mice. Keywords: disease state ...
ORGANISM(S): Mus musculus 
2007-08-29 | GSE8901 | GEO

Accurate metabolite identification remains one of the primary challenges in a metabolomics study. A reliable chemical spectral library increases the confidence in annotation, and the availability of raw and annotated data in public databases facilitates the transfer of Liquid chromatography coupl...

2019-10-30 | MTBLS1040 | MetaboLights
DDA, DIA and AIF comparison of a mixture of Natural Products.
ORGANISM(S): Unknown 
2022-01-22 | MSV000088719 | MassIVE
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