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TranscriptomicsTranscription profiling of mouse bone marrow with Aiolos and OBF-1 deletions from 7 week old mice
The chromatin regulator Aiolos and the transcriptional coactivator OBF-1 have been implicated in regulating aspects of B cell maturation and activation. Mice lacking either of these factors have a largely normal early B cell development. However, when both factors are eliminated simultaneously a blo...
ORGANISM(S): Mus musculus 
2008-11-13 | E-GEOD-12356 | biostudies-arrayexpress
TranscriptomicsAiolos regulated genes in A549, lung carcinoma cells
Analysis of transcriptional profiling change comparing A549 cells expressing control empty vector and A549 cells expressing Aiolos. Results provide insight into molecular mechanisms underlying functional consequence of ectopic expression of Aiolos in solid cancer cells. Two-condition experiment, A54...
ORGANISM(S): Homo sapiens 
2013-09-13 | E-GEOD-50812 | biostudies-arrayexpress
UnknownDisease-associated AIOLOS variants lead to immune deficiency/dysregulation by haploinsufficiency and redefine AIOLOS functional domains.
Not available
S-EPMC10836806 | biostudies-literature
UnknownAiolos regulates eosinophil migration into tissues.
Not available
S-EPMC8542574 | biostudies-literature
GenomicsA Variant in Human AIOLOS Impairs Adaptive Immunity by Interfering with IKAROS
A Variant in Human AIOLOS Impairs Adaptive Immunity by Interfering with IKAROS
PRJNA704728 | ENA
GenomicsAiolos modulates IL-15 responsiveness of intestinal intraepithelial lymphocytes [CUT&RUN]
Aiolos modulates IL-15 responsiveness of intestinal intraepithelial lymphocytes [CUT&RUN]
PRJNA908089 | ENA
GenomicsAiolos modulates IL-15 responsiveness of intestinal intraepithelial lymphocytes [RNA-seq]
Aiolos modulates IL-15 responsiveness of intestinal intraepithelial lymphocytes [RNA-seq]
PRJNA908083 | ENA
GenomicsAiolos modulates IL-15 responsiveness of intestinal intraepithelial lymphocytes [scRNA-seq]
Aiolos modulates IL-15 responsiveness of intestinal intraepithelial lymphocytes [scRNA-seq]
PRJNA908090 | ENA
GenomicsAiolos modulates IL-15 responsiveness of intestinal intraepithelial lymphocytes [ATAC-seq]
Aiolos modulates IL-15 responsiveness of intestinal intraepithelial lymphocytes [ATAC-seq]
PRJNA908082 | ENA
UnknownAiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells.
Not available
S-EPMC4070880 | biostudies-literature
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