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UnknownLocally epistatic models for genome-wide prediction and association by importance sampling.
Not available
S-EPMC5646165 | biostudies-literature
UnknownMulti-objective optimized genomic breeding strategies for sustainable food improvement.
Not available
S-EPMC6461918 | biostudies-literature
TranscriptomicsGenome Wide Profiling of p53 Response to Differentiation or DNA Damage of Human Embryonic Stem Cells
Tumor suppressor p53 promotes differentiation of human embryonic stem cells (hESCs), but an in-depth understanding of mechanism is lacking. Here, we define p53 functions in hESCs by genome wide profiling of p53 chromatin interactions and intersection with gene expression during early differentiation...
ORGANISM(S): Homo sapiens 
2013-10-18 | E-GEOD-39762 | biostudies-arrayexpress
GenomicsGenome Wide Profiling of p53 Response to Differentiation or DNA Damage of Human Embryonic Stem Cells
Tumor suppressor p53 promotes differentiation of human embryonic stem cells (hESCs), but an in-depth understanding of mechanism is lacking. Here, we define p53 functions in hESCs by genome wide profiling of p53 chromatin interactions and intersection with gene expression during early differentiation...
ORGANISM(S): Homo sapiens 
2013-10-18 | E-GEOD-39912 | biostudies-arrayexpress
TranscriptomicsMyc and SAGA Rewire an Alternative Splicing Network During Early Somatic Cell Reprogramming [Reprogramming_RNASEQ]
Embryonic stem cells are maintained in a self-renewing and pluripotent state by multiple regulatory pathways. Pluripotent-specific transcriptional networks are sequentially reactivated as somatic cells reprogram to achieve pluripotency. How epigenetic regulators modulate this process and contribute ...
ORGANISM(S): Mus musculus 
2015-04-15 | E-GEOD-67715 | biostudies-arrayexpress
GenomicsMyc and SAGA Rewire an Alternative Splicing Network During Early Somatic Cell Reprogramming [Reprogramming_ChIPSEQ]
Embryonic stem cells are maintained in a self-renewing and pluripotent state by multiple regulatory pathways. Pluripotent-specific transcriptional networks are sequentially reactivated as somatic cells reprogram to achieve pluripotency. How epigenetic regulators modulate this process and contribute ...
ORGANISM(S): Mus musculus 
2015-04-15 | E-GEOD-67694 | biostudies-arrayexpress
GenomicsMyc and SAGA Rewire an Alternative Splicing Network During Early Somatic Cell Reprogramming [mESCs_ChIPSEQ]
Embryonic stem cells are maintained in a self-renewing and pluripotent state by multiple regulatory pathways. Pluripotent-specific transcriptional networks are sequentially reactivated as somatic cells reprogram to achieve pluripotency. How epigenetic regulators modulate this process and contribute ...
ORGANISM(S): Mus musculus 
2015-04-15 | E-GEOD-67710 | biostudies-arrayexpress
UnknownAssessment of genomic prediction reliability and optimization of experimental designs in multi-environment trials.
Not available
S-EPMC8866390 | biostudies-literature
TranscriptomicsEpigenetic profiling of well differentiated and dedifferentiated liposarcoma identifies H3K9me3 and Kruppel-like factor 6 (KLF6) as determinants of aggressiveness in sarcoma (expression)
Little is known about the epigenomics of liposarcoma (LPS). Here, we profiled the global expression of 9 epigenetic marks in well differentiated (WD) and dedifferentiated (DD) LPS from 151 patients and found increased H3K9me3 among DDLPS tumors. We performed ChIP-seq and gene expression profiling ...
ORGANISM(S): Homo sapiens 
2015-08-04 | E-GEOD-57750 | biostudies-arrayexpress
UnknownSingle cell spatial profiling of the matrisome identifies region-specific adhesion and signaling networks in glioblastoma.
Not available
S-EPMC12769532 | biostudies-literature
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