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By using FACS-sorted MC1-ZE7 ES cells, we analyzed the genome-wide distribution of H3K27ac and DNA methylation in Zscan4 positive ES cells (Em+) and Zscan4 negative ES cells (Em-). H3K27 hyperacetylation and DNA demethylation were detected in heterochromatic regions of Em+ cells, but not Em- cells. ...
ORGANISM(S): Mus musculus 
We analyzed the genome-wide chromatin states in Zscan4 positive ES cells (Em+) and Zscan4 negative ES cells (Em-) by using FACS-sorted MC1-ZE7 ES cells. H3K27 hyperacetylation and DNA demethylation were detected in heterochromatic regions of Em+ cells. These results suggested that the heterochromati...
ORGANISM(S): Mus musculus 
For comprehensive human serum proteome analysis, we attempted to construct a serum spectral library for DIA-MS. Consequently, the customized spectral DIA library contained information on 23,196 peptides derived from 1,534 human serum proteins. We expect that this customized spectral DIA library will...
ORGANISM(S): Homo Sapiens (human) 
The COVID-19 pandemic is an unprecedented threat to humanity that has provoked global health concerns. Since the etiopathogenesis of this illness is not fully characterized, the prognostic factors enabling treatment decisions have not been well documented. Accurately predicting the progression of th...
ORGANISM(S): Homo Sapiens (human) 
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