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This dataset consists of 16 raw MS files, acquired on Orbitrap Fusion Lumos Tribrid mass spectrometer operated in Data Dependent Acquisition (DDA) mode for the 8 input files and DDA with simultaneous parallel reaction monitoring (targeted masses; 599.33, 604.33, 608.23, 606.33, 407.89, 403.22, 651.3...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-08 | MSV000084773 | MassIVE
Drug resistance in breast cancer is the major obstacle to a successful outcome following chemotherapy treatment. While upregulation of multidrug resistance (MDR) genes is a key component of drug resistance in multiple cancers, the complexity and hierarchy of non-MDR driven drug resistance pathways a...
ORGANISM(S): Homo sapiens 
The files are associated with a manuscript submitted for publication by Ganna Posternak et al. The main goal of this paper was functionally characterize the mechanism of action of a PROTAC designed to target BRAFV600E.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-11-07 | MSV000084551 | MassIVE
The files are associated with a manuscript submitted for publication by Ganna Posternak et al. The main goal of this paper was functionally characterize the mechanism of action of a PROTAC designed to target BRAFV600E. This dataset provides a proteome-wide view of protein degradation after treatment...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-10 | MSV000085271 | MassIVE
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