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GenomicsSF3B1 association with chromatin determines splicing outcomes
Much remains unknown concerning the mechanism by which the splicing machinery pinpoints short exons within intronic sequences and how splicing factors are directed to their pre-mRNA targets. Part of the explanation probably lies in differences in chromatin organization between exons and introns. Pro...
ORGANISM(S): Homo sapiens 
2015-04-22 | E-GEOD-65644 | biostudies-arrayexpress
TranscriptomicsExpression data from Smarcd1 knockdown R1 embryonic stem cells
We used microarrays to identify the gene expression changes after Smarcd1 knockdown in ESCs and 4 day RA differentiated ESCs Actively growing ESCs and 4d RA differentiated ESCs were harvested and RNA was extracted immediately.
ORGANISM(S): Mus musculus 
2015-03-01 | E-GEOD-65089 | biostudies-arrayexpress
TranscriptomicsExpression data from Chd1-deficient mouse ES cells (E14 cell lines) and genome-wide binding of Chd1 in parental ES cells
We used microarrays to study the effect of Chd1 loss of function in mouse ES cells. We used ChIP-chip to analyze genome-wide binding of Chd1 in normal ES cells. Mouse Embryonic Stem (ES) cells were infected with a lentiviral vector (pSicoR-mCherry) for expression of a shRNA against Chd1 and GFP (as ...
ORGANISM(S): Mus musculus 
2009-08-13 | E-GEOD-16462 | biostudies-arrayexpress
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