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TranscriptomicsAsymmetric cancer cell division regulated by AKT, Reactive Oxygen Species (ROS) high versus ROS low mRNA
Human tumors often contain slowly proliferating cancer cells that resist treatment but we do not know precisely how these cells arise. We show that rapidly proliferating cancer cells can divide asymmetrically to produce slowly proliferating “G0-like” progeny that are enriched following chemotherapy ...
ORGANISM(S): Homo sapiens 
2011-07-14 | E-GEOD-30465 | biostudies-arrayexpress
TranscriptomicsGene profiles induced by overexpression of wild-type and mutant Notch1 variants in MCF10A mammary epithelial cell line
Expression of a constitutively active Notch-1 intracellular domain (NICD) in MCF-10A cells was found to induce two distinct types of 3D structures: large, hyperproliferative structures and small, growth-arrested structures with reduced cell-to-matrix adhesion. These heterogeneous phenotypes reflect...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-20285 | biostudies-arrayexpress
UnknownProtein production and purification.
Not available
S-EPMC3178102 | biostudies-literature
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