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GenomicsThe histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3 [ChIP-Seq]
Embryonic development is tightly regulated by transcription factors and chromatin-associated proteins. H3K4me3 is associated with active transcription and H3K27me3 with gene repression, while the combination of both keeps genes required for development in a plastic state. Here we show that deletion ...
ORGANISM(S): Mus musculus 
2013-04-26 | E-GEOD-41172 | biostudies-arrayexpress
TranscriptomicsThe histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3 [Affymetrix]
Embryonic development is tightly regulated by transcription factors and chromatin-associated proteins. H3K4me3 is associated with active transcription and H3K27me3 with gene repression, while the combination of both keeps genes required for development in a plastic state. Here we show that deletion ...
ORGANISM(S): Mus musculus 
2013-04-26 | E-GEOD-41171 | biostudies-arrayexpress
TranscriptomicsHuman-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
The evolutionary expansion of the human neocortex reflects increased amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Here, we analyze the transcriptomes of distinct progenitor subpopulations isolated by a novel approach from developi...
ORGANISM(S): Homo sapiens 
2015-03-02 | E-GEOD-65000 | biostudies-arrayexpress
UnknownThe growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
Not available
S-SCDT-10_1038-S44318-024-00068-7 | biostudies-other
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