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MetabolomicsMetabolic effects of novel aldehyde dehydrogenase inhibitors (ALDH) inhibitors
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ORGANISM(S): Homo sapiens 
ST000774 | MetabolomicsWorkbench
TranscriptomicsProgenitor Cell Marker Aldehyde Dehydrogenase 1a3 Defines a Subset of Failing Pancreatic Beta Cells in Diabetic Mice
Insulin-producing beta cells become dedifferentiated during diabetes progression. An impaired ability to select substrates for oxidative phosphorylation, or metabolic inflexibility, sets the stage for progression from beta cell dysfunction to beta cell dedifferentiation. In this study, we sought to ...
ORGANISM(S): Mus musculus 
2016-09-02 | E-GEOD-78966 | biostudies-arrayexpress
TranscriptomicsRole of aldehyde dehydrogenase on the metabolic regulation in Clostridium ljungdahlii fermentation
Clostridium ljungdahlii not only utilizes CO, but also H2 as energy source during autotrophic growth. And C. ljungdahlii also grows in fructose fermentation. In theory, fructose is a more energetically favourable energy source than syngas in the fermentation of C. ljungdahlii. However, C. ljungdahli...
ORGANISM(S): Clostridium ljungdahlii 
2023-06-27 | E-MTAB-13020 | biostudies-arrayexpress
Transcriptomics2 Role of aldehyde dehydrogenase on the metabolic regulation in Clostridium ljungdahlii fermentation
Clostridium ljungdahlii can utilize CO as energy source during autotrophic growth. C. ljungdahlii grows sufficiently in CO and produces ethanol as the main product. In this study, C. ljungdahlii wild type and mutant were fermented on CO. C. ljungdahlii produced more ethanol than the ΔadhE1 mutant. T...
ORGANISM(S): Clostridium ljungdahlii 
2023-06-27 | E-MTAB-13021 | biostudies-arrayexpress
GenomicsAldehyde dehydrogenase 2 deficiency exacerbates alcohol-associated liver fibrosis
Aldehyde dehydrogenase 2 deficiency exacerbates alcohol-associated liver fibrosis
PRJNA1414450 | ENA
GenomicsGene expression data from endometrial cancer patient-derived cells (PDCs) treated with aldehyde dehydrogenase inhibitor
Gene expression data from endometrial cancer patient-derived cells (PDCs) treated with aldehyde dehydrogenase inhibitor
PRJNA524390 | ENA
GenomicsRole of aldehyde dehydrogenase on the metabolic regulation in Clostridium ljungdahlii fermentation
Role of aldehyde dehydrogenase on the metabolic regulation in Clostridium ljungdahlii fermentation
PRJEB62861 | ENA
TranscriptomicsCharacterization of aldehyde dehydrogenase 1 high ovarian cancer cells: Towards targeted stem cell therapy
Objective: The cancer stem cell (CSC) paradigm hypothesizes that successful clinical eradication of CSCs may lead to durable remission for patients with ovarian cancer. Despite mounting evidence in support of ovarian CSCs, their phenotype and clinical relevance remain unclear. We and others have f...
ORGANISM(S): Rattus norvegicus 
2016-06-02 | E-GEOD-82112 | biostudies-arrayexpress
Genomics2 Role of aldehyde dehydrogenase on the metabolic regulation in Clostridium ljungdahlii fermentation
2 Role of aldehyde dehydrogenase on the metabolic regulation in Clostridium ljungdahlii fermentation
PRJEB62864 | ENA
TranscriptomicsIdentification of Murine Uterine Genes Regulated in a Ligand-Dependent Manner by the Progesterone Receptor.
Progesterone (P4) acting through its cognate receptor, the progesterone receptor (PR), plays an important role in uterine physiology. The PR knockout (PRKO) mouse has demonstrated the importance of the P4-PR axis in the regulation of uterine function. To define the molecular pathways regulated by P4...
ORGANISM(S): Mus musculus 
2012-08-06 | E-GEOD-39920 | biostudies-arrayexpress
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