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MetabolomicsMetabolic effects of novel aldehyde dehydrogenase inhibitors (ALDH) inhibitors
Not available
ORGANISM(S): Homo sapiens 
ST000774 | MetabolomicsWorkbench
MetabolomicsPharmacological Targeting of ALDH1a2 in Dendritic Cells Enhances Antigen Presentation, T Cell Activation and Anti-tumor immunity
Dendritic cell (DC) vaccines have been proposed as cancer immunotherapies due to their role as crucial antigen-presenting cells that regulate T cell functions. Despite considerable efforts to optimize ex vivo priming of DCs, DC vaccines have rarely been successful, suggesting the presence of unknown...
2025-11-03 | MTBLS10389 | MetaboLights
TranscriptomicsExpression data from mouse ALDH1 positive and ALDH1 negative ovarian surface epithelium (OSE) cells
The hilum region of the mouse ovary, the transitional/junction area between OSE, mesothelium and tubal (oviductal) epithelium is identified as a previously unrecognized stem cell niche of the OSE. OSE cells with high ALDH1 activity have been predominantly detected in the hilum region by immunohistoc...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-43897 | biostudies-arrayexpress
GenomicsEffects of AKT/WEE1 inhibitors or ALDH inhibitor combined with PD-1 antibody on melanoma
Effects of AKT/WEE1 inhibitors or ALDH inhibitor combined with PD-1 antibody on melanoma
PRJNA818337 | ENA
UnknownA novel dithiocarbamate analogue with potentially decreased ALDH inhibition has copper-dependent proteasome-inhibitory and apoptosis-inducing activity in human breast cancer cells.
Not available
S-EPMC3671753 | biostudies-literature
TranscriptomicsEffects of AKT/WEE1 inhibitors or ALDH inhibitor combined with PD-1 antibody on melanoma
The effects of AKT/WEE1 inhibitors or ALDH inhibitor combined with PD-1 antibody on melanoma were examined. Mouse B16F10 melanoma cells were subcutaneously injected into C57/B6 mice. When tumors were well-vascularized, mice were treated with anti-PD-1, AKT I (AZD5363)+WEE1 I (MK1775), AZD5363+MK1775...
ORGANISM(S): Mus musculus 
2023-12-31 | GSE199096 | GEO
UnknownBET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.
Not available
S-EPMC5117661 | biostudies-literature
UnknownEvaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells.
Not available
S-EPMC3871589 | biostudies-literature
UnknownDevelopment of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent.
Not available
S-EPMC10763724 | biostudies-literature
UnknownIsothiocyanates (ITCs) 1-(Isothiocyanatomethyl)-4-phenylbenzene and 1-Isothiocyanato-3,5-bis(trifluoromethyl)benzene-Aldehyde Dehydrogenase (ALDH) Inhibitors, Decreases Cisplatin Tolerance and Migratory Ability of NSCLC.
Not available
S-EPMC9369118 | biostudies-literature
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