Sort   by:  
 Page size 
ModelsMosca2012 - Central Carbon Metabolism Regulated by AKT
Mosca2012 - Central Carbon Metabolism Regulated by AKT The role of the PI3K/Akt/PKB signalling pathway in oncogenesis has been extensively investigated and altered expression or mutations of many components of this pathway have been implicated in human cancers. Indeed, expression o...
2024-09-02 | BIOMD0000000426 | BioModels
TranscriptomicsRNA-seq analysis of MES-MM 98 and REN mesothelioma cell lines modulated for miR-24-3p expression
Identification of relevant miR-24-3p target mRNAs in human mesothelioma cell lines in order to characterize novel therapeutical targets in Mesothelioma disease
ORGANISM(S): Homo sapiens 
2019-02-13 | E-MTAB-7079 | biostudies-arrayexpress
TranscriptomicsMicroarray of the multiple myeloma OPM2 cell line expressing either wt FAM46C or the FAM46C-D90G mutant allele
The aim of the analysis is to compare the trascriptome of myeloma cells expressing the wt version of novel oncosuppressor FAM46C comparing it with that of cells expressing a mutant variant of the same gene often found in patients (the D90G mutant allele) or to a Mock control. Cells were grown in RP...
ORGANISM(S): Homo sapiens 
2020-10-23 | E-MTAB-8188 | biostudies-arrayexpress
TranscriptomicsRibosome profiling and RNA-seq of in vitro differentiated human CD4+ Th1 cells.
We investigated the translatome of in vitro differentiated human CD4+ Th1 cells.
ORGANISM(S): Homo sapiens 
2020-04-08 | E-MTAB-5961 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of gene expression associated to altered gene dosage of DeIF6 during eye development in Drosophila melanogaster
We investigated the transcriptome of the eye imaginal discs and retinae in wild type (GMR/+) and DeIF6 overexpressing (GMR>DeIF6) flies at the third instar larva stage and pupa 40 hours after puparium formation.
ORGANISM(S): Drosophila melanogaster 
2019-07-18 | E-MTAB-5954 | biostudies-arrayexpress
ProteomicsIntrinsic metabolic dependencies of glioblastoma tumor initiating cells dictate the sensitivity to LSD1-directed therapy
Lysine-specific histone demethylase 1A (LSD1) is an epigenetic regulator involved in several biological processes, including metabolic pathways. We established the therapeutic benefit of its pharmacological inhibition in glioblastoma (GBM) using DDP_38003 (LSD1i), which selectively targets tumor-ini...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD053770 | Pride
Lsd1 Glioblastoma 
Sort   by:  
 Page size