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ProteomicsProteomics profiling of human synovial fluid suggests global increased protein interplay in early-osteoarthritis (OA) and lost in late-stage OA
The underlying molecular mechanisms in osteoarthritis (OA) development are largely unknown. This study explores the proteome and the pairwise interplay of proteins on a global level in synovial fluid from patients with late-stage knee OA (arthroplasty), early knee OA (arthroscopy due to degenerative...
ORGANISM(S): Homo sapiens (Human) 
2022-01-27 | PXD023708 | Pride
Dia Synovial fluid Osteoarthritis 
ProteomicsExploring the early molecular pathogenesis of osteoarthritis using differential network analysis of human synovial fluid
This MS data set was used as validation data for an exploratory proteomics study of biomarkers in osteoarthritis (OA) using SOMAscan assay data. We analyzed human synovial fluid from three groups with the two methods: 1) deceased donors with mildly degenerated cartilage and/or meniscus, which is a w...
ORGANISM(S): Homo sapiens (Human) 
2024-05-13 | PXD051182 | Pride
Human Osteoarthritis Synovial fluid 
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