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TranscriptomicsVariability of gene expression profiles in human blood and lymphoblastoid cell lines
Readily accessible samples such as peripheral blood or cell lines are increasingly being used in large cohorts to characterise gene expression differences between a patient group and healthy controls. However, cell and RNA isolation procedures and the variety of cell types that make up whole blood c...
ORGANISM(S): Homo sapiens 
2011-07-25 | E-GEOD-30916 | biostudies-arrayexpress
TranscriptomicsExperimental identification of miR-378-3p targets by overexpression and silencing in murine NIH-3T3 fibroblasts
MicroRNAs (miRNAs) are short noncoding RNA molecules regulating the expression of mRNAs. Target identification of miRNAs is computationally difficult due to the relatively low homology between miRNAs and their targets. We provide data here utilizing an experimental approach to identify targets of mm...
ORGANISM(S): Mus musculus 
2012-08-07 | E-GEOD-34873 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Th1 T cell clone and anergic Th1 T cell clone made anergic by plate-bound anti-CD3 antibody
compare gene expression profiles between normal and anergic T cells and identify upregulated genes in anergic T cells Experiment Overall Design: RNA from normal Th1 T cell clone and anergic Th1 T cell clone made anergic by plate-bound anti-CD3 antibody were isolated and amplified for microarray anal...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-5960 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of A.E7 T cells to identify early growth response genes Egr-2 and Egr-3 as key negative regulators of T cell activation
pooled mRNA (2, 4, 6 hrs) from A.E7 T cells under conditions which promote or inhibit anergy induction
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2323 | biostudies-arrayexpress
ProteomicsA pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease
Addona TA, Shi X, Keshishian H, Mani DR, Burgess M, Gillette MA, Clauser KR, Shen D, Lewis GD, Farrell LA, Fifer MA, Sabatine MS, Gerszten RE, Carr SA. Nat Biotechnol. 2011, 29(7):635-43. doi: 10.1038/nbt.1899. PMCID:PMC3366591. Discovery, AIMS, and MRM datasets Discovery_Tranche_hash: b/quYtp/Q8fY...
2013-12-19 | MSV000078513 | MassIVE
GenomicsWhole Genome Scan for Pancreatic Cancer Risk in the Pancreatic Cancer Cohort Consortium and Pancreatic Cancer Case-Control Consortium (PanScan)

Within the framework of the NCI-sponsored Cohort Consortium, investigators from 12 prospective epidemiologic cohorts formed the Pancreatic Cancer Cohort Consortium in 2006. This study, also known as "PanScan", is funded by the National Cancer Institute (NCI) and involves conducting a genome-w...

phs000206.v3.p2 | EGA
ProteomicsMetrologically traceable quantification of three apolipoprotein E isoforms in cerebrospinal fluid
Apolipoprotein E (apoE) is a 317-amino-acid long glycoprotein with three common isoforms (apoE2, apoE3, and apoE4) encoded by three apoE alleles (ε2, ε3, and ε4). These polymorphic forms arise from single amino acid substitutions with Cys and Arg interchanged at positions 112 and 158 (mature protein...
ORGANISM(S): Homo Sapiens 
2023-06-13 | PXD038803 | panorama
GenomicsMOLPAGE_data - samples
Case and control samples (Genotypes)
EGAD00010000371 | EGA
GenomicsMolecular Phenotyping to Accelerate Genomic Epidemiology (MolPAGE)
MolPAGE is an integrated EU project that aims to develop methods and tools for discovery of biomarkers associated with diabetes (see www.ocdem.ox.ac.uk for MolOBB and www.twinsuk.ac.uk for MolTWIN).
EGAS00000000102 | EGA
GenomicsMolPAGE Data Access Committee
Data Access Committee EGAC01000000017
EGAC01000000017 | EGA
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