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TranscriptomicsExpression data from human skeletal muscle
Insulin is a potent pleiotropic hormone that affects processes such as cellular growth, differentiation, apoptosis, ion flux, energy expenditure, and carbohydrate, lipid, and protein metabolism. We used microarrays to detail the global programme of gene expression underlying the influence of insulin...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-22309 | biostudies-arrayexpress
MetabolomicsOverexpression of the vascular brassinosteroid receptor BRL3 confers drought resistance without penalizing plant growth

Drought represents a major threat to food security. Mechanistic data describing plant responses to drought have been studied extensively and genes conferring drought resistance have been introduced into crop plants. However, plants with enhanced drought resistance usually display lower growth, hi...

2021-05-17 | MTBLS2289 | MetaboLights
TranscriptomicsThe SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet
The prevention or delay of the onset of age-related diseases prolongs survival and improves quality of life while reducing the burden on the health care system. Activation of sirtuin 1 (SIRT1), an NAD+ deacetylase, improves metabolism and confers protection against physiological and cognitive distur...
ORGANISM(S): Mus musculus 
2014-12-20 | E-GEOD-50987 | biostudies-arrayexpress
UnknownAssociation of BMI and Cognitive Performance in the Diabetes Prevention Program Outcomes Study.
Not available
S-EPMC12636062 | biostudies-literature
TranscriptomicsEffects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Calorie restriction (CR) is the most robust non-genetic intervention to universally delay the onset of age-related diseases and extend mean and maximum lifespan. However, species, strain, sex, diet, age of onset, and level of CR are emerging as important variables to consider for a successful CR res...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-81959 | biostudies-arrayexpress
UnknownCommon variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.
Not available
S-EPMC4154629 | biostudies-literature
UnknownImpact of Parental or First-Degree Family History of Diabetes on Diabetes Incidence and Progression During Long-term Follow-up in the Diabetes Prevention Program Outcomes Study.
Not available
S-EPMC12451838 | biostudies-literature
UnknownCirculating natriuretic peptide concentrations reflect changes in insulin sensitivity over time in the Diabetes Prevention Program.
Not available
S-EPMC4158711 | biostudies-literature
UnknownConfirming glycemic status in the Diabetes Prevention Program: implications for diagnosing diabetes in high risk adults.
Not available
S-EPMC3594066 | biostudies-literature
UnknownEffects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program.
Not available
S-EPMC3439414 | biostudies-literature
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