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GenomicsHistone modification analysis in TGFbeta/TNFalpha treated A549 spheroid cultures
We studied the extent of chromatin remodeling in an in-vitro model of the epithelial-mesenchymal transition (EMT). EMT is induced in spheroid cultures (3D) using simultaneously two cytokines: TGFbeta and TNFalpha. The epithelial-mesenchymal transition (EMT) is a cellular de-differentiation process t...
ORGANISM(S): Homo sapiens 
2013-09-12 | E-GEOD-42374 | biostudies-arrayexpress
TranscriptomicsGene expression analysis in TGFbeta/TNFalpha treated A549 spheroid cultures
TGFbeta/TNFalpha treated spheroid A549 cultures are a model of the epithelial-mesenchymal transition (EMT). These experiments capture the changes in global gene expression that result from cells being induced to undergo EMT (3D control vs 3D treated), but also the differences in gene expression when...
ORGANISM(S): Homo sapiens 
2013-09-12 | E-GEOD-42373 | biostudies-arrayexpress
UnknownAssessing Technical Feasibility and Acceptability of Telehealth Palliative Care in Nursing Homes.
Not available
S-EPMC9438441 | biostudies-literature
GenomicsRemodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
Recent studies suggest a hierarchical model in which lineage-determining factors act in a collaborative manner to select and prime cell-specific enhancers, thereby enabling signal-dependent transcription factors to bind and function in a cell type-specific manner. Consistent with this model, TLR4 si...
ORGANISM(S): Mus musculus 
2013-08-09 | E-GEOD-48759 | biostudies-arrayexpress
Transcriptomicschromatin reprogramming and differential gene expression in a model of EMT (spheroid A549 treated with TGF/TNF)
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-09-12 | E-GEOD-42375 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression patterns in Clostridium thermocellum from microarray analysis of chemostat culture on cellulose or cellobiose
Earlier studies pointed to the ability of C. thermocellum to exquisitely control gene expression in response to growth rate and the presence of insoluble cellulose or soluble compounds such as cellobiose. This microarray study was carried out in order to examine expression responses of the entire g...
ORGANISM(S): Clostridium thermocellum ATCC 27405 
2010-12-15 | E-GEOD-22426 | biostudies-arrayexpress
UnknownDefining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis.
Not available
S-EPMC8514853 | biostudies-literature
MetabolomicsOverexpression of the vascular brassinosteroid receptor BRL3 confers drought resistance without penalizing plant growth

Drought represents a major threat to food security. Mechanistic data describing plant responses to drought have been studied extensively and genes conferring drought resistance have been introduced into crop plants. However, plants with enhanced drought resistance usually display lower growth, hi...

2021-05-17 | MTBLS2289 | MetaboLights
UnknownThe Intersection of Cognitive Ability and HIV: A Review of the State of the Nursing Science.
Not available
S-EPMC8091162 | biostudies-literature
ProteomicsPLpro inhibition protects in post-acute sequelae mouse model of COVID-19
The COVID-19 pandemic has highlighted how vulnerable a globally connected population is to the threat of newly emerging zoonotic viruses, exemplified by SARS-CoV-2. Despite considerable efforts to identify antivirals for coronaviruses (CoVs) in the last two decades, there exists only one FDA-approve...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-23 | PXD054356 | Pride
Sars-cov-2  long covid  pasc  inflammation 
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