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The peripheral whole-blood transcriptome analysis has been used to the identification of biomarkers in different clinical syndromes. The ability to simultaneously measure the gene expression levels of the whole transcriptome is providing a broader view of clinical syndromes such as sepsis. The aim o...
ORGANISM(S): Homo sapiens 
Abstract
BACKGROUND: Gene expression profiling (GEP) in cells obtained from peripheral blood has demonstrated to be a very useful approach for biomarker discovery and for studying molecular pathogenesis of prevalent diseases. While there is limited literature availble on gene expression markers a...
ORGANISM(S): Homo sapiens 
In this work we generated a no-letal mice model infected with pandemic H1N1 virus in order to study the mechanisms implicated in the resolution of uncomplicated pneumonia by using gene expression profiles of lung tissues.
ORGANISM(S): Mus musculus 
This project was a prospective translational study aimed at evaluating gene expression profiles (GEP) of patients with ventilator-associated pneumonia (VAP) . GEP of VAP were compared with a control group of patients which did not developed ventilator-associated lower respiratory tract infection des...
ORGANISM(S): Homo sapiens 
Background: Understanding molecular basis involved in obesity is a crucial first step in developing therapeutic strategies against excess in body weight gain Objective: The purpose of our study was to assess if obesity possess unique peripheral blood gene expression profiles, in a pilot study.
ORGANISM(S): Homo sapiens 
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