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TranscriptomicsGene expression profiles of mouse embryonic stem cells (mESCs) after genetic depletion of Id1 and knock-down of Zrf1
Id proteins are dominant negative regulators within the HLH family of proteins. In embryonic stem cells (ESCs), Id1 and Id3 maintain the pluripotent state by preventing neural differentiation. The Id1-interacting protein Zrf1 plays a crucial role as a chromatin-bound factor in specification of the n...
ORGANISM(S): Mus musculus 
2014-11-05 | E-GEOD-58627 | biostudies-arrayexpress
GenomicsZrf1 is required to establish and maintain neural progenitor identity (ChIP-Seq)
We report ChIP-seq data for Zrf1 and Ring1B occupancy in NPC Examination and comparison of DNA binding profile of Zrf1 and Ring1B in NPC
ORGANISM(S): Mus musculus 
2013-12-21 | E-GEOD-53540 | biostudies-arrayexpress
TranscriptomicsThe Polycomb protein Pcgf2/Mel18 regulates mesoderm cell fate-specification of embryonic stem cells through multiple mechanisms
Polycomb complexes are essential regulators of stem cell identity, yet very little is known about their molecular mechanisms during cell differentiation. Pcgf proteins (Pcgf1/2/3/4/5/6) are core subunits of the Polycomb repressive complex 1 (PRC1). It has been recently proposed that specific Pcgf pr...
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-67868 | biostudies-arrayexpress
TranscriptomicsZrf1 is required to establish and maintain neural progenitor identity (mRNA array)
Our work aims to characterize the role of Zrf1 in the generation and maintenance of neural progenitor cells (NPCs) Gene expression profile of shCtrl and shZrf1 cells during generation of RGC-like NPC from ESC at day 6 of neural induction. Cells were grown according to this protocol: Bibel et al, Na...
ORGANISM(S): Mus musculus 
2013-12-21 | E-GEOD-53541 | biostudies-arrayexpress
UnknownPeritoneal mesothelioma and asbestos exposure: a population-based case-control study in Italy, 2000-2021.
Not available
S-EPMC12703297 | biostudies-literature
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