The overall objective of the project is to evaluate the effects of loss of function of iron regulatory proteins (IRP1, encoded by Aco1)-1 and -2 (IRP2, encoded by Ireb2) during adult life. Mice carrying floxed Aco1 and Ireb2 alleles were crossed to a knockin strain expressing a tamoxifen-inducible C...
Here, we present a 3’-Seq dataset of ex vivo isolated mouse multipotent steady state hematopoietic stem cells (sHSC) and proliferating HSCs (16h pIC; pHSC)
RNA-Seq data from sorted bone-marrow cells corresponding to 3 different stages of neutropoiesis, obtained from 3 IRP-deficient mice and 3 control littermates (adult male mice)