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TranscriptomicsAlternate splicing in Tlr4 pathway in LPS Stimulated BMMs
Pairwise comparison of expression of alternate splicing in the Tlr4 pathway using custom designed Combimatix oligonucleotide arrays. Bone marrow derived macrophages (BMMs) from C57Bl6/J mice (6 wks male) exposed to LPS (10ng/ml) for 7hrs. Keywords: Response to LPS
ORGANISM(S): Mus musculus 
2007-01-15 | GSE4044 | GEO
TranscriptomicsThe alternative complement pathway appears to be a UVA sensor that leads to systemic immunosuppression
Ultraviolet (UV) wavebands in sunlight are immunomodulatory. About half the amount of UVA within a minimum erythemal dose of sunlight is systemically immunosuppressive, while higher doses protect from UVB immunosuppression in mice. We have previously shown that these responses to UVA are genetically...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-15618 | biostudies-arrayexpress
UnknownChitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia.
Not available
S-EPMC3359989 | biostudies-literature
TranscriptomicsELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal Via the PI3K/AKT Pathway
ELABELA (ELA) is a peptide hormone required for heart development that signals via the Apelin Receptor (APLNR, APJ). ELA is also abundantly secreted by human embryonic stem cells (hESCs), which do not express APLNR. Here we show that ELA signals in a paracrine fashion in hESCs to maintain self-rene...
ORGANISM(S): Homo sapiens 
2015-09-20 | E-GEOD-71949 | biostudies-arrayexpress
UnknownSignal Integration by Translocation and Phosphorylation of PKCδ in the B Cell Alternate Pathway.
Not available
S-EPMC8638162 | biostudies-literature
TranscriptomicsThe Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus
Pre-mRNA splicing is regulated by developmental and environmental cues, but little is known about how specific signals are transduced in mammalian cells to regulate this critical gene expression step. Here, we report massive reprogramming of alternative splicing in response to EGF signaling. By blo...
ORGANISM(S): Homo sapiens 
2012-08-17 | E-GEOD-37731 | biostudies-arrayexpress
UnknownA Novel Erythrocyte Binding Protein of Plasmodium vivax Suggests an Alternate Invasion Pathway into Duffy-Positive Reticulocytes.
Not available
S-EPMC4999553 | biostudies-literature
UnknownA novel alternate secretory pathway for the export of Plasmodium proteins into the host erythrocyte.
Not available
S-EPMC23057 | biostudies-literature
UnknownAlternate pathway for the click reaction of 2-(2-azidophenyl)-4,5-diaryloxazoles.
Not available
S-EPMC6752742 | biostudies-literature
TranscriptomicsAlternate high fat diet aggravates atherosclerosis through an IL1b-dependent reprogramming of neutrophil progenitors
Systemic immune responses induced by chronic hypercholesterolemia contribute to the initiation, progression and complications of atherosclerosis. However, the consequences of an alternate high fat diet and the associated variations in plasma cholesterol levels on atherosclerosis are unknown. To addr...
ORGANISM(S): Mus musculus 
2024-04-14 | GSE252604 | GEO
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