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TranscriptomicsSigma factor E of Mycobacterium tuberculosis controls the expression of bacterial components that modulate macrophages
Sigma factor E (SigE) controls the expression of genes that are essential for Mtb virulence. In this work, we have identified the SigE regulon during infection of macrophages Our results indicate that SigE regulates the expression of genes involved in the maintenance of Mtb cell envelope integrity a...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-25 | E-GEOD-7962 | biostudies-arrayexpress
TranscriptomicsThe global transcriptional profile of Mycobacterium tuberculosis during human macrophages infection
During lung infection Mycobacterium tuberculosis (Mtb) resides in macrophages and subverts the bactericidal mechanisms of these professional phagocytes. In this work we have analyzed by DNA microarray technique the global transcription profile of Mtb infecting primary human macrophages in order to i...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-27 | E-GEOD-6209 | biostudies-arrayexpress
UnknownA Novel Pathogenic Variant in the MN1 Gene in a Patient Presenting with Rhombencephalosynapsis and Craniofacial Anomalies, Expanding MN1 C-terminal Truncation Syndrome.
Not available
S-EPMC10421676 | biostudies-literature
UnknownStructural insights into the antibacterial function of the Pseudomonas putida effector Tke5
Not available
S-SCDT-10_1038-S44318-025-00689-6 | biostudies-other
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
TranscriptomicsSepsis Express IG
The peripheral whole-blood transcriptome analysis has been used to the identification of biomarkers in different clinical syndromes. The ability to simultaneously measure the gene expression levels of the whole transcriptome is providing a broader view of clinical syndromes such as sepsis. The aim o...
ORGANISM(S): Homo sapiens 
2014-03-15 | E-MTAB-1548 | biostudies-arrayexpress
UnknownThe impact of health and wellness coaching on patient-important outcomes in chronic illness care: A systematic review and meta-analysis.
Not available
S-EPMC10964774 | biostudies-literature
TranscriptomicsThe sigma factor E of Mycobacterium tuberculosis modulates the inflammatory response of human THP1 cells
Mycobacterium tuberculosis (Mtb) is well adapted to survive in macrophages and usually subverts the bactericidal mechanisms of these professional phagocytes. The adaptation of Mtb to the intracellular life depends on its ability to regulate the expression of its genes. Among the most important bact...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-7870 | biostudies-arrayexpress
TranscriptomicsThe sigma factor E of Mycobacterium tuberculosis modulates the inflammatory response of macrophages
Mycobacterium tuberculosis (Mtb) is well adapted to survive in macrophages and usually subverts the bactericidal mechanisms of these professional phagocytes. The adaptation of Mtb to the intracellular life depends on its ability to regulate the expression of its genes. Among the most important bact...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-7871 | biostudies-arrayexpress
UnknownDedifferentiation-derived neural stem cells exhibit perturbed temporal progression
Not available
S-SCDT-10_15252-EMBR_202255837 | biostudies-other
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