Alveolar epithelial cell

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Organisms

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Caenorhabditis elegans (1)
Triticum aestivum (1)

Organisms

Mus musculus (322)
Homo sapiens (238)
Rattus norvegicus (11)
Sus scrofa (4)
Mycobacterium tuberculosis (2)
Euarchontoglires (1)
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Mus musculus musculus (1)
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Repository

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pride (67)
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dbGaP (1)
EVA (1)
GNPS (1)
PAXDB (1)

Tissue

Lung (29)
Epithelial cell (26)
Cell culture (16)
Epithelial cell of lung (5)
Alveolar epithelial cell line (4)
Fibroblast (4)
Type II pneumocyte (3)
Macrophage (3)
Primary cell (3)
Stem cell (2)
Basal cell (1)
IMR-90 cell (1)
Mammary epithelium (1)
Neoplastic cell (1)
Alveolar system (1)
Endothelial cell (1)
Mammary gland (1)
Tissue (1)
Fibroblast of lung (1)
Extracellular vesicle (1)
Mesenchymal cell (1)
Heart (1)
Bronchoalveolar lavage (1)
Embryo (1)
Permanent cell line cell (1)
Liver (1)
Blood (1)

Disease

Normal (6)
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COVID-19 (3)
Idiopathic pulmonary fibrosis (2)
Chronic obstructive pulmonary disease (2)
Influenza (2)
Breast cancer (2)
Disease free (2)
Lung Cancer (1)
Perilobar nephrogenic rest (1)
Asthma (1)
Xenografts with H1299 cell line (1)
Cancer (1)
Hypertensive (1)
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Prostate carcinoma (1)
Adenocarcinoma (1)
Ovarian cancer (1)
Carcinoma (1)
Interstitial lung disease (1)
Aspergillosis (1)
Severe acute respiratory syndrome coronavirus 2 (1)
Coronavirus infectious disease (1)
Severe acute respiratory syndrome (1)
Adult respiratory distress syndrome (1)
Lung cancer (1)
Respiratory syncytial virus infectious disease (1)
Cystic fibrosis (1)
Wounds and Injuries (1)

Technology Type

Mass Spectrometry (67)
Shotgun proteomics (39)
Bottom-up proteomics (15)
Data-dependent acquisition (9)
Affinity purification coupled with mass spectrometry proteomics (6)
Data-independent acquisition (5)
Mass spectrometry (4)
Mass spectrometry assay (2)
SWATH MS (2)
Gel-based experiment (2)
NMR spectroscopy (1)
HDMSE (1)
SRM/MRM (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (20)
Illumina HiSeq 4000 (8)
Q Exactive (5)
NextSeq 500 (4)
Orbitrap Fusion Lumos (4)
Illumina HiSeq 2500 (3)
LTQ Velos (3)
Orbitrap Eclipse (3)
Agilent G2505B scanner (2)
Illumina HiSeq 1500 (2)
LTQ Orbitrap Velos Pro (2)
LTQ Orbitrap Velos (2)
Bravo automated liquid handling robot station (Agilent) (1)
NEXTflex Small-RNA Seq kit v3 (Perkin Elmer) & NEXTflex Rapid XP DNA-seq kit v2 (Perkin Elmer) (1)
Direct-zol RNA microprep kit (Zymo Research), LabChip RNA pico sensitivity assay, Perkin Elmer & Nucleospin RNA kit (Macherey Nagel) (1)
PALM type 4 microscope (Zeiss) (1)
Mastercycler pro S Thermocyler (Eppendorf); 2100 Bioanalyzer (Agilent) (1)
2100 Bioanalyzer (Agilent); Axio Imager.Z2 (ZEISS) (1)
CryoStar NX70 Cryostat (Epredia) (1)
Affymetrix GeneChip(R) HT Scanner (1)
Affymetrix GeneChip Scanner 3000 7G (1)
Illumina HiScanSQ (1)
G2565BA DNA microarray scanner [Agilent] (1)
Scanning hardware (1)
Axon GenePix 4000B scanning hardware (1)
Illumina NovaSeq X (1)
NA (1)
NextSeq 2000 (1)
DNBSEQ-G400 (1)
MinION (1)

Publication Date

2026 (99)
2013 (92)
2024 (89)
2021 (88)
2025 (86)
2012 (82)
2015 (76)
2011 (74)
2014 (73)
2010 (70)
2020 (62)
2022 (58)
2023 (57)
2016 (49)
2008 (48)
2018 (33)
2019 (32)
2009 (22)
2007 (21)
2017 (17)
2006 (4)
2005 (3)
2004 (1)
2002 (1)

UNIPROT ID/AC

LAMB3_MOUSE (1)
COLQ_MOUSE (1)
CFA53_MOUSE (1)
MMP9_MOUSE (1)
S6A14_MOUSE (1)
LOXL3_MOUSE (1)
CFA57_MOUSE (1)
SG3A2_MOUSE (1)
ABCA5_MOUSE (1)
CC151_MOUSE (1)
Q80UR4_MOUSE (1)
SPAT6_MOUSE (1)
S39A8_MOUSE (1)
MCPT8_MOUSE (1)
SP17_MOUSE (1)
VGFR1_MOUSE (1)
DLRB2_MOUSE (1)
LFNG_MOUSE (1)
PAR6B_MOUSE (1)
D3YVL2_MOUSE (1)
MIEAP_MOUSE (1)
GRAA_MOUSE (1)
CFA69_MOUSE (1)
C1QT2_MOUSE (1)
CLC1A_MOUSE (1)
M4A4D_MOUSE (1)
MUC1_MOUSE (1)
SPA6L_MOUSE (1)
CC181_MOUSE (1)
SEM3E_MOUSE (1)

CHEBI ID

CHEBI:15428 (2)
CHEBI:53577 (1)
CHEBI:15368 (1)
CHEBI:40448 (1)
CHEBI:23042 (1)
CHEBI:16881 (1)
CHEBI:24266 (1)
CHEBI:33942 (1)
CHEBI:35619 (1)
CHEBI:21803 (1)
CHEBI:29987 (1)
CHEBI:29995 (1)
CHEBI:17822 (1)
CHEBI:26271 (1)
CHEBI:25094 (1)
CHEBI:18237 (1)
CHEBI:27570 (1)
CHEBI:18186 (1)
CHEBI:26986 (1)
CHEBI:18295 (1)
CHEBI:17234 (1)
CHEBI:28300 (1)
CHEBI:18257 (1)
CHEBI:16708 (1)
CHEBI:506227 (1)
CHEBI:17562 (1)
CHEBI:16283 (1)
CHEBI:16977 (1)
CHEBI:24898 (1)
CHEBI:25017 (1)

Metabolite Name

Isoleucine (2)
Spermine (2)
Indole-3-acetic acid (2)
Adenosine (2)
1-Methylguanine (2)
Cytidine (2)
Hypoxanthine (2)
Chlorogenic Acid Methyl Ester (1)
SM 9:1;2O/26:1 (1)
N'2-acetylpyridine-2-carbohydrazide (1)
SM 8:1;2O/28:1 (1)
SM 14:3;2O/9:0 (1)
PC 17:0_18:0 (1)
PC O-33:7 (1)
PC O-41:6 (1)
LDGCC 22:5 (1)
PC O-41:4 (1)
N1-pyrazin-2-yl-4-chlorobenzamide (1)
LPC O-20:2 (1)
PC 42:5_44:12 (1)
N-{6-[4-(tert-butyl)phenoxy]-3-pyridinyl}-N'-(2-thienyl)urea (1)
N-[methyl(oxo)phenyl-lambda~6~-sulfanylidene]-N'-phenylurea (1)
N-benzoyl-N'-(2-chlorophenyl)thiourea (1)
SM 15:3;2O/18:5 (1)
SM 8:1;2O/30:2 (1)
PC O-36:10 (1)
PC 18:0_18:0 (1)
SM 9:1;2O/26:6 (1)
SM 38:6;3O (1)
SM 8:1;2O/36:5 (1)

First Public Date

2026 (103)
2024 (100)
2021 (73)
2025 (70)
2023 (56)
2022 (53)
2020 (49)
2014 (40)
2018 (31)
2019 (26)
2017 (16)
2015 (10)
2016 (5)
2013 (3)

Modelling Approach

Boolean model (1)
Ordinary differential equation model (1)

Study status

Active, not recruiting (1)

Lab affiliation

Medizinisches Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany (3)
Functional Genomics, University Medicine Greifswald, Germany (2)
Signalling ISP, Babraham Institute, Cambridge, UK (2)
Dalian Institute of Chemical Physics, Chinese Academy of Sciences (2)
Department of Pediatrics, UMCG/RUG, Groningen, The Netherlands (2)
Icahn School of Medicine at Mount Sinai (2)
Systems Biology Ireland, University College Dublin (2)
Baxter Laboratory for Stem Cell Biology Department of Microbiology & Immunology Stanford University School of Medicine 269 Campus Drive CCSR 3205b Stanford, CA 94305-5175, USA (1)
Center for Network Systems Biology, Boston University (1)
Comprehensive Pneumology Center (CPC), University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany (1)
Department: Department of Microbiology and Immunology Lab: Host and Pathogen Interactivity Lab Institute: National University of Singapore Country: Singapore (1)
Center for Regenerative Medicine, Boston University and Boston Medical Center, Boston, MA 02118, USA The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA (1)
Proteomics Unit Spanish National Cancer Research Center (CNIO) 28029 Madrid Spain (1)
Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, Boston, MA 02118, USA (1)
Center for Network Systems Biology, Boston University, USA (1)
MRC Protein Phosphorylation and Ubiquitylation Unit, Sir James Black Centre, Dow Street, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK (1)
Department of Internal Medicine Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA (1)
Transplantation Center, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China (1)
Clinical Proteomics, Medizinisches Proteom-Center, Ruhr-Universität Bochum, Universitätsstraße 150, 44801 Bochum, Germany. (1)
Systems Immunology Department, The Merbl Lab, Weizmann Institute of Science, Israel (1)
University of North Carolina, Chapel Hill. Department of Environmental Sciences and Engineering (ENVR; Institute for Environmental Health Solutions (IEHS; UNC Superfund Research Program (UNC-SRP; Center for Environmental Medicine and Lung Biology (CEMALB; Curriculum in Toxicology & Environmental Medicine (CiTEM) (1)
1Institute of Lung Health and Immunity, Comprehensive Pneumology Center Munich with the CPC-M bioArchive, Helmholtz Center Munich, Research Center for Environmental Health, Member of the German Center of Lung Research (DZL), Germany (1)
Division of Applied Functional Genomics, German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany. (1)
Laboratorio de Referencia e Investigacion en Micologia, National Centre for Microbiology, Instituto de Salud Carlos III (1)
Division of Infection Medicine, BMC Faculty of Medicine Lund University Lund, Sweden (1)
Lung Repair & Regeneration Department, Boehringer Ingelheim Pharma GmbH & Co. KG (1)
Department of Biotechnology and Biomedicine, Technical University of Denmark (1)
CNRS UMR 5249, Laboratory of Chemistry and Biology of Metals, Grenoble, France (1)
Professor, Gerald Bronfman Department of Oncology, McGill University, Montréal, Quebec, H3G 1Y6, Canada (1)
Murdoch Children's Research Institute, Melbourne, Australia (1)

Keyword

Ipilimumab (1)
Nivolumab (1)

IsPrivate

False (3)

Submitter Keywords

COVID-19 (1)

Classification

bacteria (2)

Study type

Transcription profiling by array (433)
RNA-seq of coding RNA (44)
Comparative genomic hybridization by array (32)
Unknown experiment type (13)
ChIP-seq (13)
RNA-seq of non coding RNA (11)
RNA-seq of coding RNA from single cells (10)
Methylation profiling by array (9)
Transcription profiling by RT-PCR (8)
Other (7)
ChIP-chip by tiling array (3)
Human - One-color microarray (3)
RNA-seq of total RNA (3)
Transcription profiling by SAGE (2)
Transcription profiling by tiling array (2)
ChIP-chip by array (2)
Genotyping by array (2)
Spatial transcriptomics by high-throughput sequencing (2)
Animal - One-color microarray (1)
Cell line - One-color microarray (1)
Cell line - High-throughput sequencing (1)
ATAC-seq (1)
RIP-seq (1)
MicroRNA profiling by array (1)
Genotyping by high throughput sequencing (1)
Methylation profiling by high throughput sequencing (1)
Interventional (1)

Release Date

2022 (268)
2021 (227)
2023 (216)
2025 (214)
2020 (177)
2024 (160)
2013 (136)
2015 (134)
2011 (128)
2014 (127)
2019 (125)
2012 (118)
2016 (114)
2010 (104)
2017 (102)
2018 (95)
2008 (63)
2009 (50)
2026 (37)
2007 (34)
2005 (14)
2006 (10)
2004 (5)
2003 (4)
2002 (3)
2001 (2)
1998 (1)

Location

Guam (1)
United States (1)

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PCR array of inflammatory cytokines and receptors in mouse lungs with NF-kappaB RelA mutant in alveolar epithelial cells during LPS stimulation

A murine model of RelA mutated throughout the alveolar epithelium was generated. Mice were anesthetized and intratracheally instilled with 50M-NM-

ORGANISM(S): Mus musculus

2012-08-03 | E-GEOD-38398 | biostudies-arrayexpress

PCR array of inflammatory cytokines and receptors in mouse lungs with NF-kappaB RelA mutant in alveolar epithelial cells during pneumococcal pneumonia

A murine model of RelA mutated throughout the alveolar epithelium was generated. Mice were anesthetized and intratracheally instilled with 106 CFU of Streptococcus pneumoniae serotype 3 into the left lung lobe. Mice were euthanized after 15 hours after instillation, and left lung lobes were collecte...

ORGANISM(S): Mus musculus

2012-08-03 | E-GEOD-38399 | biostudies-arrayexpress

Human alveolar hydrogels promote morphological and transcriptional differentiation in iPSC-derived alveolar type 2 epithelial cells

Alveolar type 2 epithelial cells (AT2s) derived from human induced pluripotent stem cells (iAT2s) have rapidly contributed to our understanding of AT2 function and disease. However, as iAT2s are primarily cultured in three-dimensional (3D) Matrigel, a matrix derived from cancerous mouse tissue, it i...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2023-03-10 | MSV000091470 | MassIVE

Transcriptomes of Alveolar epithelial cells

Freshly isolated type I and type II alveolar epithelial cells were investigated for transcriptomes with dual-color DNA microarray using 3DNA 50 kit.

ORGANISM(S): Rattus norvegicus

2010-06-11 | E-GEOD-2160 | biostudies-arrayexpress

Acquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells

Our data show that Wnt and FGF signalling, and the downstream transcription factors NKX2.1 and TFAP2C, promote human alveolar or airway fate respectively. Moreover, we have functionally validated cell-cell interactions in human lung alveolar patterning. We show that Wnt signalling from differentiati...

ORGANISM(S): Homo sapiens

2022-02-28 | E-MTAB-11435 | biostudies-arrayexpress

Transcriptome in alveolar epithelial type II-like cells differentiated from human lung progenitor cells

Resident stem/progenitor cells in lungs are important for tissue homeostasis and repair. We isolated human lung progenitor cells and named alveolar epithelial progenitor cells (AEPCs)(Fujino N, et al. 2011. Lab Invest. 91:363). AEPCs have phenotypes of both alveolar epithelial type II (ATII) cells a...

ORGANISM(S): Homo sapiens

2012-10-11 | E-GEOD-33825 | biostudies-arrayexpress

Expression data of influenza A-infected human type I-like alveolar epithelial cells

Pandemic influenza H1N1 (pdmH1N1) virus causes mild disease in humans but occasionally leads to severe complications and even death, especially in those who are pregnant or have underlying disease. Cytokine responses induced by pdmH1N1 viruses in vitro are comparable to other seasonal influenza viru...

ORGANISM(S): Homo sapiens

2010-10-06 | E-GEOD-24533 | biostudies-arrayexpress

Transcription profiling of human alveolar epithelial cells stimulated with TNF-alpha

Transcriptional Profiling of Human Alveolar Epithelial Cells stimulated with TNF-alpha

ORGANISM(S): Homo sapiens

2010-04-16 | E-TABM-686 | biostudies-arrayexpress

Human alveolar epithelial cells (A549) exposed to cigarette smoke extract

Human alveolar epithelial cells were exposed to cigarette smoke extract (CSE) for 1, 3 and 5 weeks at 1%, 5% and 10%, and gene expression was evaluated by complete transcriptome microarrays. In this study we explored the effect of cigarette smoke on the gene expression profile. Human alveolar epith...

ORGANISM(S): Homo sapiens

2016-02-16 | E-GEOD-77942 | biostudies-arrayexpress

Transcription profiling of rat freshly-isolated alveolar epithelial type I cells, freshly-isolated type II cells, and type II cells cultured for 7 days

Comparison of rat freshly-isolated alveolar epithelial type I cells, freshly-isolated type II cells, and type II cells cultured for 7 days

ORGANISM(S): Rattus norvegicus

2007-11-01 | E-GEOD-1567 | biostudies-arrayexpress

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