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TranscriptomicsTranscriptional Profiling Analysis of Host response to Clostridium perfringens Infection in Broilers
Necrotic enteritis is a disease caused by Clostridium perfringens, which threatens poultry production in the absence of dietary antibiotics. A total number of 144 Ross broilers were reared in 12 pens with each hosting 12 birds. Each 6 pens of birds were fed medicated (bacitracin at 55 ppm) or non-m...
ORGANISM(S): Gallus gallus 
2010-06-25 | E-GEOD-13085 | biostudies-arrayexpress
TranscriptomicsIndices of Tolerance (IOT): Cross-platform biomarkers that identify kidney transplant tolerance
Being able to identify patients in whom immunological tolerance has been established or is developing would allow an individually tailored approach to post-transplant management of kidney allograft recipients. Ex vivo immunological monitoring was performed on samples from five groups of European ren...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-14655 | biostudies-arrayexpress
TranscriptomicsFeedback amplication of fibrosis through matrix stiffening and COX-2 suppression
We tested the hypothesis that increasing matrix stiffness on which normal human lung fibroblasts are grown promotes the expression of a fibrogenic cellular transcriptomic program. Keywords: Human lung fibroblast, matrix stiffness, PTGS2, COX-2, Prostaglandin E2 Total RNA extracted from normal human...
ORGANISM(S): Homo sapiens 
2010-07-15 | E-GEOD-22011 | biostudies-arrayexpress
TranscriptomicsRybp ChIP-chip in mouse ES cells
Rybp binding in wild-type, Eed-KO, and Dnmt1-KO ES cells ChIP on chip analysis was carried out using the Mouse Promoter ChIP-on-chip Microarray Set (G4490A, Agilent-014716 and Agilent-014717, Palo Alto, Calif., USA). ESCs were subjected to ChIP assay using a Rybp antibody (Santa Cruz; H-115). Purifi...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-32289 | biostudies-arrayexpress
TranscriptomicsExpression data from wild type (WT) and TREM2 null alveolar macrophages (AM)
TREM-2 has been described to be a phagocytic receptor. We assessed the influence of TREM-2 on gene expression in alveolar macrophages (AM) In this data-set we characterised the differences in basal gene expression using affymetrix mouse 1.0 ST arrays between WT and TREM2-/- AM and observed TREM2 -/-...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-51378 | biostudies-arrayexpress
TranscriptomicsExpression data from wild-type and Rybp-deficient ES cells
We used microarrays to investigate a global change in gene expression by conditional depletion of Rybp in mouse ES cells. Total RNAs were extracted from wild-type and Rybp-deficient ES cells, and were subjected to microarray analysis using Affymetrix GeneChip Mouse Genome 430A 2.0 arrays
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-32287 | biostudies-arrayexpress
TranscriptomicsGene expression profile in Yaf2 KD and/or RYBP KO ES cells.
Gene expression change by Yaf2 KD in wild type or RYBP KO ES cells. Total RNAs were extracted from the respective ES cells, and were subjected to microarray analysis using Affymetrix GeneChip Mouse Genome 430A 2.0 arrays
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-32288 | biostudies-arrayexpress
TranscriptomicsExpression regulation by RYBP in mouse embryonic stem cells
Polycomb repressive complexes (PRCs) are important chromatin regulators of ES cell function. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B, and has been suggested to participate in localizing Polycomb complexes to their targets. Moreover, constitutive inactivation of RYBP precludes...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-32294 | biostudies-arrayexpress
UnknownThe global, regional, and national burden of cancer, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12687902 | biostudies-literature
UnknownGlobal, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
Not available
S-EPMC10356620 | biostudies-literature
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