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MetabolomicsUntargeted In Silico Compound Classification - A Novel Metabolomics Method to Assess the Chemodiversity in Bryophytes

In plant ecology, biochemical analyses of bryophytes and vascular plants are often conducted on dried herbarium specimen as species typically grow in distant and inaccessible locations. Here, we present an automated in silico compound classification framework to annotate metabolites using an unta...

2026-01-30 | MTBLS851 | MetaboLights
UnknownChenopodium ambrosioides L. Reduces Synovial Inflammation and Pain in Experimental Osteoarthritis.
The chronicity of osteoarthritis (OA), characterized by pain and inflammation in the joints, is linked to a glutamate receptor, N-methyl-D-aspartate (NMDA). The use of plant species such as Chenopodium ambrosioides L. (Amaranthaceae) as NMDA antagonists offers a promising perspective. This work aims...
S-EPMC4629912 | biostudies-literature
UnknownLINE-1 methylation in granulocyte DNA and trihalomethane exposure is associated with bladder cancer risk.
DNA methylation changes contribute to bladder carcinogenesis. Trihalomethanes (THM), a class of disinfection by-products, are associated with increased urothelial bladder cancer (UBC) risk. THM exposure in animal models produces DNA hypomethylation. We evaluated the relationship of LINE-1 5-methylcy...
S-EPMC4622716 | biostudies-literature
TranscriptomicsGene expression in CF-vs-non CF human airway epithelial cell samples obtained by nasal brushing.
A small-scale whole genome microarray study of gene expression in human native nasal epithelial cells from F508del-CFTR homozygous CF patients and non-CF controls. We used the custom designed Affymetrix HsAirwaya520108F Arrays to compare gene expression in 5 CF and 5 non CF nasal epithelial cell sam...
ORGANISM(S): Homo sapiens 
2013-04-10 | E-GEOD-40445 | biostudies-arrayexpress
UnknownNutrient-driven growth and microbiome shifts in the brown alga Sargassum fluitans III.
Since 2011, holopelagic Sargassum has been accumulating in a region of the tropical Atlantic now referred to as the Great Atlantic Sargassum Belt (GASB). Among the hypothesized contributors to these accumulations are the increased inputs of nitrogen (N) and phosphorus (P) in the tropical Atlantic Oc...
S-EPMC12351368 | biostudies-literature
UnknownEvaluation of multidrug-resistant bacteria and their molecular mechanisms found in small animal veterinary practices in Portugal.

Introduction

Intensive medical care provided in companion animal practices carries the potential risk of selecting and disseminating multidrug-resistant organisms (MDROs). However, data on infection, prevention and control standards specific to small animal veterinary practices (SAVPs) remai...
S-EPMC12086164 | biostudies-literature
UnknownLINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk.

Background

Aberrant global DNA methylation is shown to increase cancer risk. LINE-1 has been proven a measure of global DNA methylation. The objectives of this study were to assess the association between LINE-1 methylation level and bladder cancer risk and to evaluate effect modification by...
S-EPMC3992509 | biostudies-literature
UnknownCOVID-19 vaccination rate and willingness of an additional dose among inflammatory bowel disease patients receiving biologic therapy: Fearless and with desire.
Effective vaccines against the SARS-CoV-2 are already available and offer a promising action to control the COVID-19 pandemic. IBD patients on biological agents accept the vaccine as well as an additional dose if recommended.

Background

Vaccination against COVID-19 prevents its severe forms a...
S-EPMC9123800 | biostudies-literature
UnknownOccurrence of Methicillin-Resistant Staphylococcus spp. on Brazilian Dairy Farms that Produce Unpasteurized Cheese.
Methicillin-resistant Staphylococcus spp. (MRS) have been identified in several foods, including dairy products. Studies are needed about their occurrence and genetic diversity in the dairy production chain in order to gain a better understanding of their epidemiology and control. This study therefo...
S-EPMC7762534 | biostudies-literature
UnknownMolecular Xenomonitoring (MX) allows real-time surveillance of West Nile and Usutu virus in mosquito populations.
West Nile Virus (WNV) and Usutu virus (USUV) circulate through complex cryptic transmission cycles involving mosquitoes as vectors, birds as amplifying hosts and several mammal species as dead-end hosts. Both viruses can be transmitted to humans through mosquito bites, which can lead to neuroinvasiv...
S-EPMC11709297 | biostudies-literature
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