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UnknownReining in BTK: Interdomain Interactions and Their Importance in the Regulatory Control of BTK.
Not available
S-EPMC8260988 | biostudies-literature
UnknownThe Conformational State of the BTK Substrate PLCγ Contributes to Ibrutinib Resistance.
Not available
S-EPMC8924901 | biostudies-literature
UnknownScreening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase.
Not available
S-EPMC12126845 | biostudies-literature
UnknownImpact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia.
Not available
S-EPMC11677227 | biostudies-literature
UnknownConformational switches that control the TEC kinase - PLCγ signaling axis.
Not available
S-EPMC8803661 | biostudies-literature
UnknownSubstrate recognition of PLCγ1 via a specific docking surface on Itk.
Not available
S-EPMC3880187 | biostudies-literature
UnknownAchieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts.
Not available
S-EPMC5629114 | biostudies-literature
UnknownScaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation.
Not available
S-EPMC4540666 | biostudies-literature
UnknownAn Autoinhibitory Role for the Pleckstrin Homology Domain of Interleukin-2-Inducible Tyrosine Kinase and Its Interplay with Canonical Phospholipid Recognition.
Not available
S-EPMC5956896 | biostudies-literature
UnknownA conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase.
Not available
S-EPMC4188691 | biostudies-literature
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