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ProteomicsDysregulated Proteolysis of Extracellular Matrix Proteins Regulates Influenza and Pneumonia Co-infection Associated Mortality
The balance between tissue integrity and efficient immune response is critical for host survival. Here we investigate the role of extra cellular matrix (ECM)-remodeling events in the lung during influenza infection. Using an unbiased genomic and proteomic approach we follow the dynamics of gene and ...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-19 | PXD004871 | Pride
Influenza Pneumonia Extracellular matrix proteins 
TranscriptomicsControl of breast cancer growth and initiation by the stem cell-associated transcription factor TCF3
Regulatory factors controlling stem cell identity and self-renewal are often active in aggressive cancers and are thought to promote their growth and progression. TCF3 (also known as TCF7L1) is a member of the TCF/LEF transcription factor family that is central in regulating epidermal and embryonic ...
ORGANISM(S): Homo sapiens 
2012-10-23 | E-GEOD-38893 | biostudies-arrayexpress
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