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ProteomicsAmorphous silica nanoparticle exposures can lead to mitochondrial protein changes
Mitochondrial fractions from J774 mouse macrophage/monocyte cells were exposed to amorphous silica nanoforms and mitochondrial protein profiles were examined to gain information on relative toxicities of these nanomaterials on mitochondrial pathways and identify potency determinants, for risk charac...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-22 | PXD027593 | Pride
Proteomics Mass spectrometry Exposure Physicochemical characteristics Mitochondria Amorphous silica nanomaterials Nanoforms 
ProteomicsResponses of macrophages to repeated exposures to different forms of amorphous silica
Synthetic amorphous silica (SAS) is a nanomaterial used in a wide variety of applications, including the use as a food additive. Two types of SAS are commonly employed as a powder additive, precipitated silica and fumed silica. Numerous studies have investigated the effects of synthetic amorphous si...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-09 | PXD030002 | Pride
Macrophage Mouse Lc-ms/ms 
TranscriptomicsSilica nanoparticles effects on gene expression of A549 cells
Expansion of nanotechnology will bring many potential benefits as adversely effects on human health. Protection of the human respiratory system from exposure of volatile nanoparticles has become an emerging health concern. The understanding of the biological processes involved in the development and...
ORGANISM(S): Homo sapiens 
2014-09-08 | E-GEOD-53700 | biostudies-arrayexpress
UnknownAmorphous Quantum Nanomaterials.
Not available
S-EPMC6440210 | biostudies-literature
TranscriptomicsTranscriptional responses to engineered nanoplatforms for drug delivery in primary human aortic endothelial cells.
This study evaluated transcriptional effects of nanomaterials that have been proposed for use as platforms for drug delivery. We tested SiO2 that had been surface modified to have a positive zetapotential of different geometries as well PAMAM dendrimers with different surface charges. We tested thes...
ORGANISM(S): Homo sapiens 
2013-12-20 | E-GEOD-35142 | biostudies-arrayexpress
UnknownSimultaneous amorphous silica and phosphorus recovery from rice husk poultry litter ash.
Not available
S-EPMC8695335 | biostudies-literature
UnknownIs aggregated synthetic amorphous silica toxicologically relevant?
Not available
S-EPMC6942297 | biostudies-literature
TranscriptomicsNanomaterials trigger functional responses in primary human immune cells
Targeting the immune system with nanoparticles (NPs) to deliver immunomodulatory molecules emerged as a solution to address intra-tumoral immunosuppression and enhance therapeutic response. While the potential of nanoimmunotherapies in reactivating immune cells has been evaluated in several preclini...
ORGANISM(S): Homo sapiens 
2024-11-15 | E-MTAB-14550 | biostudies-arrayexpress
UnknownNonlinear Elasticity of Amorphous Silicon and Silica from Density Functional Theory.
Not available
S-EPMC11648081 | biostudies-literature
UnknownEffects of Ultrasonic Dispersion Energy on the Preparation of Amorphous SiO₂ Nanomaterials for In Vitro Toxicity Testing.
Not available
S-EPMC6359325 | biostudies-literature
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