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TranscriptomicsAn Integrated Network of Androgen Receptor and TMPRSS2-ERG Gene Fusion in Prostate Cancer Progression
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-14097 | biostudies-arrayexpress
TranscriptomicsAn Integrated Network of Androgen Receptor and TMPRSS2-ERG Gene Fusion in Prostate Cancer Progression (II)
Androgen receptor (AR) is a transcription factor that plays a central role in the growth and development of the normal prostate and its malignant transformation. More recently, a majority of prostate cancers have been shown to harbor recurrent gene fusions of the androgen-regulated gene, TMPRSS2, t...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-14092 | biostudies-arrayexpress
GenomicsChIP-Seq analysis of ER binding sites in MCF7 breast cancer cells
Estrogen Receptor (ER) is a hormonal transcription factor that plays important roles in breast cancer. It functions primarily through binding to the regulatory regions of target genes containing the consensus ERE motifs. In order to identify ER target genes and re-define the ERE motifs we performed...
ORGANISM(S): Homo sapiens 
2010-02-01 | E-GEOD-19013 | biostudies-arrayexpress
UnknownFOXA1 inhibits hypoxia programs through transcriptional repression of HIF1A.
Not available
S-EPMC9464719 | biostudies-literature
UnknownTRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression.
Not available
S-EPMC6258673 | biostudies-literature
TranscriptomicsSuz12 ChIP-chip using Avi-6k-hu
The polycomb group (PcG) protein, EZH2, possesses oncogenic properties for which the underlying mechanism is unclear. In this set of experiments, we sought to identify a robust set of Suz12-occupied gene promoters in prostate cancer cell lines. Genome-wide location analysis (ChIP-chip) of SUZ12 was ...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-5596 | biostudies-arrayexpress
UnknownPolycomb-Mediated Disruption of an Androgen Receptor Feedback Loop Drives Castration-Resistant Prostate Cancer.
Not available
S-EPMC5243151 | biostudies-literature
TranscriptomicsAndrogen receptor-independent function of FoxA1 in prostate cancer metastasis
FoxA1 has been shown critical for prostate development and prostate-specific gene expression regulation. In addition to its well-established role as an AR pioneering factor,several studies have recently revealed significant AR binding events in prostate cancer cells with FoxA1 knockdown. Furthermore...
ORGANISM(S): Homo sapiens 
2013-04-05 | E-GEOD-37314 | biostudies-arrayexpress
GenomicsPioneer factor FOXA1 defines GATA2- and AR-mediated transcriptional program in prostate cancer
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-01-11 | E-GEOD-69045 | biostudies-arrayexpress
GenomicsFoxA1 inhibits androgen receptor expression and suppresses prostate cancer metastasis [DU145, ChIP-seq]
FoxA1 has been shown critical for prostate development and prostate-specific gene expression regulation. In addition to its well-established role as an AR pioneering factor,several studies have recently revealed significant AR binding events in prostate cancer cells with FoxA1 knockdown. Furthermore...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-47987 | biostudies-arrayexpress
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