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MetabolomicsEnergy-translation coupling limits yeast anaerobic growth

This study employs yeast as a model system to thoroughly investigate the differences in regulatory mechanisms under various nutrient limitation conditions, utilizing a systems biology approach integrated with techniques such as multi-omics analysis.To obtain a comprehensive quantitative landscap...

2026-05-24 | MTBLS14573 | MetaboLights
MetabolomicsA phosphoketolase bypasses reductive stress in P. aeruginosa under anaerobic survival

Across diverse contexts, bacteria experience loss of electron acceptors due to fluctuating environmental conditions, requiring strategies to avoid metabolic arrest due to reductive stress. Yet, microbial metabolism has been primarily studied with cells growing aerobically under nutrient replete c...

2026-06-03 | MTBLS13293 | MetaboLights
MetabolomicsThe murine lung microbiome is dysbalanced by the human pathogenic fungus Aspergillus fumigatus resulting in enrichment of anaerobic bacteria
Here, we report significant changes in the composition of the lung microbiome and metabolome of mice under immune suppression, infection of immunosuppressed mice with virulent and avirulent strains of the clinically important human-pathogenic fungus Aspergillus fumigatus, and treatment with the clin...
2025-07-04 | MTBLS12262 | MetaboLights
TranscriptomicsEffects of vitamin B12 on the gene expression of PAO1 under anaerobic growth conditions
Pseudomonas aeruginosa undergoes cell elongation and forms robust biofilms during anaerobic respiratory growth using nitrate (NO3-) as an alternative electron acceptor. Understanding the mechanism of cell shape change induced upon anaerobiosis is crucial to the development of effective treatments ag...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2012-06-17 | E-GEOD-34836 | biostudies-arrayexpress
ProteomicsFumarate effect on the Escherichia coli proteome at aerobic and anaerobic growth conditions
The changes in protein composition of E. coli were studied in a global proteomic approach for aerobic growth without or with fumarate as carbon source (glycerol + O2, fumarate + O2, respectively) and anaerobic growth without or with fumarate as carbon source (glycerol + DMSO, glycerol + DMSO + fumar...
ORGANISM(S): Escherichia coli 
2019-11-20 | PXD011760 | Pride
Escherichia coli  fumarate metabolism Aerobic/anaerobic growth  c4-dicarboxylates Lc-udmse 
TranscriptomicsAnaerobic Oxidation of Benzene by the Hyperthermophilic Archaeon Ferroglobus placidus (Phenol vs. Benzoate)
Anaerobic benzene oxidation coupled to the reduction of Fe(III) was studied in Ferroglobus placidus in order to learn more about how such a stable molecule could be metabolized under strict anaerobic conditions. F. placidus conserved energy to support growth at 85°C in a medium with benzene provide...
ORGANISM(S): Ferroglobus placidus DSM 10642 
2011-07-19 | E-GEOD-28549 | biostudies-arrayexpress
TranscriptomicsAnaerobic Oxidation of Benzene by the Hyperthermophilic Archaeon Ferroglobus placidus (Benzene vs. Acetate)
Anaerobic benzene oxidation coupled to the reduction of Fe(III) was studied in Ferroglobus placidus in order to learn more about how such a stable molecule could be metabolized under strict anaerobic conditions. F. placidus conserved energy to support growth at 85°C in a medium with benzene provide...
ORGANISM(S): Ferroglobus placidus DSM 10642 
2011-07-19 | E-GEOD-30798 | biostudies-arrayexpress
TranscriptomicsAnaerobic Oxidation of Benzene by the Hyperthermophilic Archaeon Ferroglobus placidus (Benzene vs. Phenol)
Anaerobic benzene oxidation coupled to the reduction of Fe(III) was studied in Ferroglobus placidus in order to learn more about how such a stable molecule could be metabolized under strict anaerobic conditions. F. placidus conserved energy to support growth at 85°C in a medium with benzene provide...
ORGANISM(S): Ferroglobus placidus DSM 10642 
2011-07-19 | E-GEOD-30799 | biostudies-arrayexpress
TranscriptomicsAnaerobic Oxidation of Benzene by the Hyperthermophilic Archaeon Ferroglobus placidus (Benzene vs. Benzoate)
Anaerobic benzene oxidation coupled to the reduction of Fe(III) was studied in Ferroglobus placidus in order to learn more about how such a stable molecule could be metabolized under strict anaerobic conditions. F. placidus conserved energy to support growth at 85°C in a medium with benzene provide...
ORGANISM(S): Ferroglobus placidus DSM 10642 
2011-07-19 | E-GEOD-30801 | biostudies-arrayexpress
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
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