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MetabolomicsFaecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems, however, evidence of their direct impact on cognitive functions is still lacking. We tested whe...

2021-12-17 | MTBLS1437 | MetaboLights
ProteomicsTargeted mass spectrometry quantification of total soy protein residues from commercially processed ingredients for food allergen management
Soybean is one of the most commonly allergenic foods in the U.S., and the ubiquity and variety of commercial soy ingredients in the food industry make it a challenging allergen to avoid. The processing methods used to produce soy-derived ingredients result in protein modifications that often substan...
ORGANISM(S): Glycine Max 
2021-03-29 | PXD022639 | panorama
ProteomicsProteomic Evidence of Dietary Sources in Ancient Dental Calculus
Archaeological dental calculus has emerged as a rich source of ancient biomolecules, including proteins. Previous analyses of proteins extracted from ancient dental calculus revealed the presence of the dietary milk protein β-lactoglobulin, providing direct evidence of dairy consumption in the archa...
ORGANISM(S): Homo sapiens (Human) 
2018-07-18 | PXD009603 | Pride
Human Dental calculus Dental plaque Lc-ms/ms 
ProteomicsProteomic investigation of organic residues from ancient Baħrija pottery reveals dietary habits during Maltese Bronze Age
The impressive increase of performance and versatility of the MS-instrumentation, which today represents an indispensable tool in proteomics, has determined a considerable growth of the so-called paleoproteomics as interdisciplinary approach, which involve chemists, archaeologists, and evolutionary ...
ORGANISM(S): Bos taurus (Bovine) Triticum aestivum (Wheat) Hordeum vulgare (Barley) 
2021-02-25 | PXD022848 | Pride
Paleoproteomic Ancient food proteins High-resolution mass spectrometry Deamidation 
ProteomicsUse of Proteomics for Dietary Reconstruction: a Case Study using Animal Teeth from Ancient Mesopotamia
This research examines animal teeth from Early Dynastic (2900-2350 BC) Mesopotamia (Southern Iraq) to assess animal management practices and identify consumption patterns in animal diets. The objective to answer larger questions about food management and environmental resilience in ancient early com...
ORGANISM(S): environmental samples <mammals> 
2025-03-24 | PXD050140 | Pride
Ancient mesopotamia Dietary reconstruction Osteological animal Animal teeth proteomics 
ProteomicsCurated cauldrons: Preserved proteins from early copper alloy vessels illuminate feasting practices in the steppe
Analysis of residues from ancient Maykop cauldrons to examine food preparation and serving traditions.
ORGANISM(S): Ovis aries 
2023-10-24 | PXD040519 | Pride
Cauldrons Proteomics Steppe Ancient proteins Maykop 
ProteomicsRelief Food Subsistence Revealed by Microparticle and Proteomics Analyses of Dental Calculus From Victims of the Great Irish Famine
Food and diet were class markers in nineteenth-century Ireland, which became evident as nearly one million people, primarily the poor and destitute, died as a consequence of the notorious Great Famine of 1845–1852. Famine took hold after a blight (Phytophthora infestans) destroyed the only means of ...
ORGANISM(S): Homo sapiens (Human) 
2019-10-17 | PXD015002 | Pride
Bioarchaeology  microparticle  lc-ms/ms  proteomics  starch  tartar  teeth  calculus 
ProteomicsDairying supported prehistoric occupation of the highland Tibetan Plateau
The extreme environments of the Tibetan Plateau offer significant challenges to human survival, demanding novel adaptations. While the role of biological and agricultural adaptations in enabling early human colonization of the plateau has been widely discussed, the contribution of pastoralism is les...
ORGANISM(S): Homo sapiens (Human) 
2023-03-15 | PXD028538 | Pride
Tibetan plateau Paleoproteomics High-altitude adaptation Dairy pastoralism 
ProteomicsHuman dental calculus LC-MS/MS
The purpose of this study was to investigate oral microbiome and host proteins in archaeological human dental tissues using a shotgun proteomics approach. The research focuses on dental calculus (mineralized plaque), dentine, a carious lesion, and an alveolar bone abscess from the medieval site of D...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Homo Sapiens (ncbitaxon:9606) Ovis (ncbitaxon:9935) 
2016-10-23 | MSV000080279 | MassIVE
ProteomicsDirect evidence of milk consumption from ancient human dental calculus, UK
This study investigated the consumption of milk products in the archaeological record, utilizing human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia. Protein extraction and generation of tryptic peptides from dental calculus was performed using a ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-04 | MSV000080221 | MassIVE
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