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TranscriptomicsGnHR agonist trigger versus hCG trigger in final ovulation induction
The objective of this experiment was to explore differences in follicle transcriptomes in patients having oocyte maturation induced with either a bolus of hCG or a GnRH agonist. Upon oocyte retrieval, mural granuloasa cells and cumulus cells were isolated, allowing for comparison of the follicular t...
ORGANISM(S): Homo sapiens 
2013-06-15 | E-MTAB-1670 | biostudies-arrayexpress
TranscriptomicsNon-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer
We used Illumina Infinium 27k Human DNA Methylation BeadChip v1.2 to assess genome-wide DNA methylation profiling of normal colon epithelial, adenomas and colorectal adenocarcinomas across approximately 27,000 CpGs in fresh frozen colorectal tissue samples. We found that cancer-associated methylatio...
ORGANISM(S): Homo sapiens 
2013-06-15 | E-GEOD-40055 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human primary colorectal cancers
Samples were taken from colorectal cancers in surgically resected specimens from 74 patients. The expression profiles were determined using Affymetrix Human Genome U133Plus 2.0 arrays. Our MSI/MSS classifer was applied to these samples. Experiment Overall Design: mRNA from 74 fresh-frozen primary co...
ORGANISM(S): Homo sapiens 
2009-01-16 | E-GEOD-13067 | biostudies-arrayexpress
GenomicsThe Potential Role of Alu Y in the Development of Resistance to SN38 (Irinotecan) or Oxaliplatin in Colorectal Cancer
Purpose: Irinotecan (SN38) and oxaliplatin are chemotherapeutic agents used in the treatment of colorectal cancer. However, the frequent development of resistance to these drugs represents a considerable challenge in the clinic. Alus as retrotransposons comprise 11% of the human genome. Genomic toxi...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-56269 | biostudies-arrayexpress
UnknownNew-onset atrial fibrillation and chronic coronary syndrome in the CLARIFY registry.
Not available
S-EPMC10834159 | biostudies-literature
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