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MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
UnknownAR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase.
Not available
S-EPMC8433584 | biostudies-literature
UnknownCompositional zero-inflated network estimation for microbiome data.
Not available
S-EPMC7768662 | biostudies-literature
UnknownDiet modification and metformin have a beneficial effect in a fly model of obesity and mucormycosis.
Not available
S-EPMC4182538 | biostudies-literature
UnknownNew strategies in squamous cell carcinoma of the lung: identification of tumor drivers to personalize therapy.
Not available
S-EPMC3737591 | biostudies-literature
TranscriptomicsA six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma
A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma Pancreatic ductal adenocarcinoma (PDAC), comprising over 90% of all pancreatic cancers, remains a lethal disease with an estimated 232,000 new cases, 227,000 deaths per year worldwide, and a less than ...
ORGANISM(S): Homo sapiens 
2010-07-18 | E-GEOD-21501 | biostudies-arrayexpress
UnknownBayesian inference of hub nodes across multiple networks.
Not available
S-EPMC6393214 | biostudies-literature
UnknownTumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes.
Not available
S-EPMC7288240 | biostudies-literature
UnknownImatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin.
Not available
S-EPMC4878082 | biostudies-literature
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