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Unknown
(51)
Genomics
(37)
Proteomics
(3)
Transcriptomics
(2)
Metabolomics
(1)
Organisms
Homo sapiens
(33)
Organisms
Mus musculus
(9)
Repository
EGA
(28)
ENA
(9)
pride
(3)
biostudies-arrayexpress
(2)
MetaboLights
(1)
Tissue
Cell culture
(1)
Pancreatic islet beta cell
(1)
Type B pancreatic cell
(1)
Type B pancreatic cell differentiation
(1)
Disease
Type 1 diabetes mellitus
(2)
Technology Type
Mass Spectrometry
(3)
Data-dependent acquisition
(2)
AB SOLiD 4 System, Illumina HiSeq 2500, Illumina HiSeq 2000, AB SOLiD System 3.0
(1)
NMR spectroscopy
(1)
Affinity purification coupled with mass spectrometry proteomics
(1)
Gel-based experiment
(1)
Immunopeptidomics
(1)
Shotgun proteomics
(1)
Instrument Platform
10X Genomics Chromium
(1)
N/A
(1)
Illumina HiSeq 4000
(1)
Bruker
(1)
Publication Date
2025
(2)
2026
(1)
2012
(1)
2018
(1)
2023
(1)
CHEBI ID
CHEBI:15344
(1)
CHEBI:15354
(1)
CHEBI:15355
(1)
CHEBI:15366
(1)
CHEBI:15428
(1)
CHEBI:15603
(1)
CHEBI:15611
(1)
CHEBI:15891
(1)
CHEBI:15971
(1)
CHEBI:16024
(1)
CHEBI:16236
(1)
CHEBI:16335
(1)
CHEBI:16344
(1)
CHEBI:16414
(1)
CHEBI:16643
(1)
CHEBI:16737
(1)
CHEBI:16857
(1)
CHEBI:16870
(1)
CHEBI:16919
(1)
CHEBI:16977
(1)
CHEBI:17170
(1)
CHEBI:17191
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CHEBI:17196
(1)
CHEBI:17203
(1)
CHEBI:17268
(1)
CHEBI:17295
(1)
CHEBI:17301
(1)
CHEBI:17549
(1)
CHEBI:17712
(1)
CHEBI:17754
(1)
Metabolite Name
3-Hydroxybutyric acid
(1)
3-Hydroxyisovaleric acid
(1)
5-Aminolevulinic acid
(1)
Acetic acid
(1)
Acetoacetic acid
(1)
Acetylcholine
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Adenosine
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Ethanol
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Formic acid
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Glucaric acid
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Glycerol
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Glycerophosphocholine
(1)
Glycine
(1)
Guanidoacetic acid
(1)
Isopropyl alcohol
(1)
L-Alanine
(1)
L-Asparagine
(1)
L-Glutamine
(1)
L-Histidine
(1)
L-Isoleucine
(1)
L-Lactic acid
(1)
First Public Date
2018
(8)
2019
(1)
Study type
Transcription profiling by array
(1)
RNA-seq of coding RNA from single cells
(1)
Release Date
2022
(7)
2019
(7)
2018
(6)
2025
(5)
2020
(5)
2023
(4)
2021
(3)
2026
(2)
2012
(2)
2016
(2)
2015
(2)
2014
(2)
2010
(2)
2024
(1)
2013
(1)
2011
(1)
2007
(1)
Lab affiliation
Alitea Biotechnology GmbH
(1)
Department of Biochemistry and Pharmacology, School of Biomedical Sciences, The University of Melbourne, Australia
(1)
Justus-Liebig-University Giessen
(1)
Tags
xref:PubMed:29899446
(8)
xref:PubMed:30635236
(1)
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Tim-3 mediates T cell trogocytosis to limit antitumor immunity.
Not available
S-EPMC9057587
|
biostudies-literature
Cite
T-bet, a Th1 transcription factor regulates the expression of Tim-3.
Not available
S-EPMC2837127
|
biostudies-literature
Cite
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.
Not available
S-EPMC2118637
|
biostudies-literature
Cite
An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction.
Not available
S-EPMC4311884
|
biostudies-literature
Cite
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy.
Not available
S-EPMC7864927
|
biostudies-literature
Cite
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.
Not available
S-EPMC3099570
|
biostudies-literature
Cite
Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.
Not available
S-EPMC3401220
|
biostudies-literature
Cite
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Not available
S-EPMC4297519
|
biostudies-literature
Cite
T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice.
Not available
S-EPMC2889349
|
biostudies-literature
Cite
TIM-3 restrains anti-tumour immunity by regulating inflammasome activation.
Not available
S-EPMC8627694
|
biostudies-literature
Cite
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