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TranscriptomicsTranscription profiling of mouse embryonic stem cells transfected with miR-10a or miR-10a-MUT shows that miR-10a interacts with the 5 prime untranslated region of mRNAs encoding ribosomal proteins and enhances their translation
MicroRNAs (miRNAs) are small RNAs that function as post-transcriptional regulators of gene expression. miRNAs affect a variety of signaling pathways and impaired miRNA regulation may contribute to the development of cancer and other diseases. We show that miRNA miR-10a interacts with the 5' untransl...
ORGANISM(S): Mus musculus 
2008-11-08 | E-MEXP-1375 | biostudies-arrayexpress
TranscriptomicsThe fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes
Background/Objectives: Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many sm...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-58622 | biostudies-arrayexpress
ProteomicsTartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection
During airway infection, upregulation of proinflammatory cytokines and subsequent immune cell recruitment is essential to mitigate bacterial infection. Conversely, during prolonged and non-resolving airway inflammation, neutrophils contribute to tissue damage and remodeling. This occurs during disea...
ORGANISM(S): Homo sapiens (Human) 
2022-12-30 | PXD038135 | Pride
Nf‐b Copd Acp5 Spp1 Trap5 Pseudomonas aeruginosa Cystic fibrosis 
Unknown31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts : National Harbor, MD, USA. 9-13 November 2016
Not available
S-EPMC5260784 | biostudies-literature
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