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TranscriptomicsMicroarray gene expression analysis of T-cell prolymphocytic leukemia (T-PLL) patient samples
T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive neoplasm of mature T-cells with an urgent need for rationally designed therapies to address its notoriously chemo-refractory behavior. To characterize the gene expression profiles, 12 T-PLL MNC samples (>90% tumor cell content) were scr...
ORGANISM(S): Homo sapiens 
2017-09-08 | E-MTAB-5916 | biostudies-arrayexpress
TranscriptomicsFurin deficiency efect on T cells
Analysis of T-cells lacking the proprotein convertase furin. Proprotein convertases promote the proteolytic maturation of proproteins. Furin is induced in activated T-cells. Results provide insight into the function of furin in T-cells. CD4+CD62L+CD44- naive, CD4+CD62L-CD44+ memory and CD4+CD25+FoxP...
ORGANISM(S): Mus musculus 
2015-08-05 | E-GEOD-67884 | biostudies-arrayexpress
TranscriptomicsAndersson_et_al_2013
LGL leukemia is chronic clonal lymphoproliferative disorder, characterized by expansion of cytotoxic CD8+ T-cells or NK-cells. We compared gene expression of 2 LGL leukemia patients with STAT3 mutation (Patients 11 and 12) and 2 LGL leukemia patients without STAT3/STAT5b mutation (Patients 9 and 10)...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-MTAB-2068 | biostudies-arrayexpress
ProteomicsCell wall proteome of Tuwongella immobilis
Bacteria of the Planctomycetes phylum have many unique cellular features, such as extensive membrane invaginations and the ability to import macromolecules. These features raise intriguing questions about the composition of their cell envelopes. In this study, we have used microscopy, phylogenomics ...
ORGANISM(S): Tuwongella immobilis Bacteria 
2020-08-10 | PXD019121 | Pride
Planctomycetes Tuwongella immobilis Cell wall Lc-ms/ms 
TranscriptomicsRajala_et_al_2013
Large lymphocytic leukemia (LGL) is a chronic clonal lymphoproliferative disorder, characterized by expansion of cytotoxic CD8+ T-cells or NK-cells. We compared gene expression of 3 LGL leukemia patients with STAT3 mutation (Patients 1, 2, and 3), 3 LGL leukemia patients with STAT5b mutation (Patien...
ORGANISM(S): Homo sapiens 
2013-04-15 | E-MTAB-1611 | biostudies-arrayexpress
UnknownDesign of glycopeptides used to investigate class II MHC binding and T-cell responses associated with autoimmune arthritis.
Not available
S-EPMC3058040 | biostudies-literature
UnknownStaphylococcus aureus convert neonatal conventional CD4(+) T cells into FOXP3(+) CD25(+) CD127(low) T cells via the PD-1/PD-L1 axis.
Not available
S-EPMC3930383 | biostudies-literature
UnknownComplementarity-determining region clustering may cause CAR-T cell dysfunction.
Not available
S-EPMC10415375 | biostudies-literature
UnknownSynthetic oleanane triterpenoids suppress MYB oncogene activity and sensitize T-cell acute lymphoblastic leukemia cells to chemotherapy.
Not available
S-EPMC10106619 | biostudies-literature
UnknownAutologous engineered T cell receptor therapy in advanced cancer.
Not available
S-EPMC10732691 | biostudies-literature
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