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TranscriptomicsComparison of miRNA expression in Dickkopf1-expressing versus control newborn mouse skin
miRNA expression was compared in skin from control newborn mice and littermate mice ectopically expressing the potent secreted WNT inhibitor Dickkopf 1 (DKK1) in the epidermis. DKK1 completely suppresses hair follicle development. Multiple miRNAs were identified that reproducibly produced signals ab...
ORGANISM(S): Mus musculus 
2010-06-11 | E-GEOD-4723 | biostudies-arrayexpress
TranscriptomicsEsophageal keratinocyte invasion after loss of E-cadherin and TGF receptor type II
Esophageal cancer is one of the deadliest cancers as patients present at late stages of disease. Frequent gene alterations include the loss of E-cadherin and TGFb receptor type II. The goal of this study was to establish a model of esophageal cancer by introducing dominant-negative mutants of E-cadh...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-19472 | biostudies-arrayexpress
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