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MetabolomicsAndrogens drive SLC1A5-dependent metabolic reprogramming in polycystic ovary syndrome-GC-MS analysis of KGN cells

Polycystic ovary syndrome (PCOS) is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression of PCOS. However, the underlying mechanism remains unclear. In this study, we conducted targeted...

2025-04-14 | MTBLS12370 | MetaboLights
MetabolomicsAndrogens drive SLC1A5-dependent metabolic reprogramming in polycystic ovary syndrome-GC-MS analysis of follicular fluid
Polycystic ovary syndrome (PCOS) is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression of PCOS. However, the underlying mechanism remains unclear. In this study, we conducted targeted me...
2025-04-14 | MTBLS12371 | MetaboLights
MetabolomicsAndrogens drive SLC1A5-dependent metabolic reprogramming in polycystic ovary syndrome-LC-MS analysis of granulosa cells

Polycystic ovary syndrome (PCOS) is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression of PCOS. However, the underlying mechanism remains unclear. In this study, we conducted targeted...

2025-04-14 | MTBLS12367 | MetaboLights
TranscriptomicsHormones, Genes, and Athleticism: Effect of Androgens on the Avian Muscular Transcriptome
Male vertebrate social displays vary from physically simple to complex, with the latter involving exquisite motor command of the body and appendages. Studies of these displays have, in turn, provided substantial insight into neuromotor mechanisms. The neotropical golden-collared manakin (Manacus vit...
ORGANISM(S): Taeniopygia guttata 
2016-03-30 | E-GEOD-73660 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of testis from Sertoli cell-selective androgen receptor knockout mice and wild type mice to unravel the molecular mechanisms mediating the effects of androgens on spermatogenesis
To unravel the molecular mechanisms mediating the effects of androgens on spermatogenesis, testicular gene expression was compared in mice with a Sertoli cell-selective androgen receptor knockout (SCARKO) and littermate controls on postnatal d 10. At this age testicular cell composition is still com...
ORGANISM(S): Mus musculus 
2007-09-25 | E-GEOD-2260 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of testis from Sertoli cell-selective androgen receptor knockout mice and wild type mice to unravel the molecular mechanisms mediating the effects of androgens on spermatogenesis
To unravel the molecular mechanisms mediating the effects of androgens on spermatogenesis, testicular gene expression was compared in mice with a Sertoli cell-selective androgen receptor knockout (SCARKO) and littermate controls on postnatal d 10. At this age testicular cell composition is still com...
ORGANISM(S): Mus musculus 
2007-09-25 | E-GEOD-2259 | biostudies-arrayexpress
UnknownAndrogens and Their Role in Regulating Sex Differences in the Hypothalamic/Pituitary/Adrenal Axis Stress Response and Stress-Related Behaviors.
Not available
S-EPMC8744007 | biostudies-literature
GenomicsAndrogens increase excitatory neurogenic potential in human brain organoids
Androgens increase excitatory neurogenic potential in human brain organoids
PRJNA777692 | ENA
TranscriptomicsThe effect of androgens on CD4 T-cells
The hormonal milieu influences immune tolerance as well as the immune response against viruses and cancer, but the direct effect of androgens on cellular immunity remains largely uncharacterized. We therefore sought to evaluate the effect of androgens on murine CD4 T-cells by micro-array analysis Ma...
ORGANISM(S): Mus musculus 
2014-05-16 | E-GEOD-54945 | biostudies-arrayexpress
TranscriptomicsGene Expression Profile of Androgen Modulated Genes in the Murine Fetal Developing Lung
Accumulating evidences suggest that sex affects lung development. During the fetal period, male lung maturation is delayed compared with female and surfactant production appears earlier in female than in male fetal lungs. We analyzed by microarrays the expression of genes showing a sexual difference...
ORGANISM(S): Mus musculus 
2010-01-14 | E-GEOD-18135 | biostudies-arrayexpress
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