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TranscriptomicsExpression data from mouse tissue Angiotensin II treated for 0,1,3,7days
Angiotensin II (Ang II) mediated signaling plays a key role in the development of hypertension associated target organ damages. However, the gene expression changes regulated by Ang II in the early stage of acute cerebral, cardiac, renal, vascular injury remain unclear. we investigated Ang IIâ??medi...
ORGANISM(S): Mus musculus 
2014-07-16 | E-GEOD-59437 | biostudies-arrayexpress
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
TranscriptomicsMitochondrial functional aberrations in a mouse model of non-ischemic heart failure
We characterized the metabolic and cardiac mitochondrial function in a mouse model of non-ischemic HF. Inhibition of nitric oxide synthesis and hypertension, which often present together, are two important risk factors in human non-ischemic HF. Compared with L-NAME L-NG-Nitroarginine methyl ester (L...
ORGANISM(S): Mus musculus 
2016-01-19 | E-GEOD-72132 | biostudies-arrayexpress
TranscriptomicsmiRNAs expression profiling from mouse heart after Ang II (angiotensin II) (1500ng/kg/min) infusion for 3 days and 7 days
Angiotensin II stimulates fibroblast proliferation and substantially alters gene expression patterns leading to cardiac remodeling, but the mechanisms for such differences are unknown. MicroRNAs are a novel mechanism for gene expression regulation. Herein we tested the miRNAs patterns in mouse heart...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-69559 | biostudies-arrayexpress
UnknownEvidence for a Physiological Mitochondrial Angiotensin II System in the Kidney Proximal Tubules: Novel Roles of Mitochondrial Ang II/AT1a/O2- and Ang II/AT2/NO Signaling.
Not available
S-EPMC7299167 | biostudies-literature
UnknownTargeting GPR39 in structure-based drug discovery reduces Ang II-induced hypertension.
Not available
S-EPMC11538459 | biostudies-literature
UnknownScoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress.
Not available
S-EPMC7957216 | biostudies-literature
ProteomicsA proteomic characterization reveals differences in the milk fat globule membrane of buffalo and bovine milk
The proteins of the milk fat globule membrane (MFGM) have a number of functions, such as the regulation of milk fat secretion and metabolism, the uptake and transportation of fatty acids in the intestine and potential protection from bacterial or viral infection. While the proteome of the MFGM in bo...
ORGANISM(S): Bos taurus (Bovine) Bubalus bubalis 
2017-05-19 | PXD005318 | Pride
Xanthine oxidase Proteomics Buffalo milk Milk fat globule membrane Lc-ms/ms 
UnknownUPLC-MS-Based Serum Metabolomics Reveals Potential Biomarkers of Ang II-Induced Hypertension in Mice.
Not available
S-EPMC8131677 | biostudies-literature
UnknownHuoxue Qianyang Qutan recipe attenuates Ang II-induced cardiomyocyte hypertrophy by regulating reactive oxygen species production.
Not available
S-EPMC8549094 | biostudies-literature
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