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ProteomicsTK SILACepedia - Reprogramming of the tyrosine kinase-regulated proteome in breast cancer by combined use of RNAi and SILAC quantitative proteomics
Tyrosine kinases (TKs) are central regulators in cellular activities and perturbations of TK signaling contribute to oncogenesis. However, less than half of the TKs have been thoroughly studied and a global functional analysis of their proteomic portrait is lacking. Here we conducted a combined appr...
ORGANISM(S): Homo sapiens (Human) 
2015-06-23 | PXD002065 | Pride
Silac tyrosine kinases breast cancer cell signaling 
ProteomicsLMTK3 Represses Tumour Suppressor-Like Genes through Chromatin Remodeling in Breast Cancer
LMTK3 is an oncogenic receptor tyrosine kinase (RTK) implicated in various types of cancer including breast, lung, gastric and colorectal. It is localized in different cellular compartments but its nuclear function has not been investigated thus far. We have mapped LMTK3 binding across the genome us...
ORGANISM(S): Homo sapiens (Human) 
2019-10-30 | PXD002399 | Pride
Lmtk3 chromatin breast cancer 
OtherReprogramming of the tyrosine kinase-regulated proteome in breast cancer by combined use of RNAi and SILAC quantitative proteomics
Data from ProteomeXchange, PXD ID: PXD002065. File: GS-45.mzml. Published as part of Mol Cell Proteomics. 2015 Jun 18 . From the Abstract: {{i}} ... Tyrosine kinases (TKs) are central regulators in cellular activities and perturbations of TK signaling contribute to oncogenesis. However, less than h...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320016092 | GPMDB
Resource Reanalysis 
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