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TranscriptomicsExpression data from mouse tissue Angiotensin II treated for 0,1,3,7days
Angiotensin II (Ang II) mediated signaling plays a key role in the development of hypertension associated target organ damages. However, the gene expression changes regulated by Ang II in the early stage of acute cerebral, cardiac, renal, vascular injury remain unclear. we investigated Ang IIâ??medi...
ORGANISM(S): Mus musculus 
2014-07-16 | E-GEOD-59437 | biostudies-arrayexpress
ProteomicsMolecular mechanisms underlying the antitumoral effects of Angiotensin-(1-7) in the A549 cell line
Angiotensin-(1-7) [Ang-(1-7)] is a heptapeptide of the renin-angiotensin system (RAS) with antitumoral effects reported in various tumoral cell lines, including the lung adenocarcinoma A549. While previous studies have shown that Ang-(1-7) modulates MAPK and PI3K-AKT signaling, the precise molecular...
ORGANISM(S): Homo sapiens (Human) 
2026-01-26 | PXD066687 | Pride
A549 cell line Renin-angiotensin system Angiotensin-(1-7) 
TranscriptomicsHigh-throughput sequencing of endogenous small RNAs from rat vascular smooth muscle cells with and without Angiotensin II stimulation
Angiotensin II (Ang II)-mediated vascular smooth muscle cells (VSMC) dysfunction plays a critical role in cardiovascular diseases. However, the role of microRNAs (miRNAs) in this process is unclear. We used small RNA deep sequencing to profile Ang II-regulated miRNAs in rat VSMC and evaluated their ...
ORGANISM(S): Rattus norvegicus 
2012-03-23 | E-GEOD-35664 | biostudies-arrayexpress
TranscriptomicsQTL for renal and cardiac function during Angiotensin II and high-sodium treatment of a backcross between C57BL/6J-to-Balb/CJ-F1 and Balb/CJ
Balb/CJ mice develop heart failure and quickly decompensate during combination treatment with Angiotensin II and high-sodium diet, while C57BL/6J mice do not. Balb/CJ show a predominantly diastolic heart failure, signs of increased pulmonary pressure, relative sodium and fluid retention, peripheral ...
ORGANISM(S): Mus musculus 
2019-06-13 | E-MTAB-8047 | biostudies-arrayexpress
TranscriptomicsC.Nahmias_MDA231_Ang
Human breast cancer cells (MDA-MB-231) were cultured in serum-free conditions and either left untreated or treated for 24h in presence of 100nM Angiotensin II. Total RNA was extracted using trizol and reverse transcribed prior to analysis.
ORGANISM(S): Homo sapiens 
2012-12-05 | E-MEXP-3470 | biostudies-arrayexpress
UnknownThe Role of Angiotensin–(1-7) in Cancer
Not available
S-EPMC7122233 | biostudies-literature
ProteomicsQuantitative proteomics and Real-Time PCR reveal downregulation of CXCR4 as a downstream effect of angiotensin-(1-7) treatment after experimental myocardial infarction
Angiotensin-(1-7) (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system. The cardioprotective role of Ang-(1-7) has been described due to its anti-inflammatory and anti-fibrotic activities. In this context, we investigated the impact of the oral formulation of Ang-(1-7) vehicul...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-08-19 | PXD012896 | Pride
Proteomics Inflammation Mass spectrometry Heart Angiotensin-(1-7) Myocardial infarction 
TranscriptomicsAngiotensin II induced aneurysms in male ApoE mice
In this study we used microarrays to examine relative genes expression within the aorta of ApoE-/- infused with angiotensin II in relation to aneurysm formation. Infusion of angiotensin II induces aortic dilatation particularly of the suprarenal aorta in ApoE-/- mice. Based on studies carried out in...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-12591 | biostudies-arrayexpress
TranscriptomicsMyoblast stimulation with angiotensin II
Quiescent C2C12 myoblasts and myoblasts that were stimulated with Angiotensin II for 12 h or 24 h Keywords = Angiotensin II
ORGANISM(S): Mus musculus 
2004-07-28 | E-GEOD-1592 | biostudies-arrayexpress
TranscriptomicsIdentification of angiotensin II-responsive genes in the kidney
In order to characterize gene expression networks linked to AT1 angiotensin receptors in the kidney, we carried out genome-wide transcriptional analysis of RNA from kidneys of wild-type (WT) and AT1A receptor-deficient mice (KOs) at baseline and after 2 days of angiotensin II infusion (1 ug/kg/min)...
ORGANISM(S): Mus musculus 
2010-09-30 | E-GEOD-18430 | biostudies-arrayexpress
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