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MetabolomicsComparison of intestinal microbes and metabolites in active VKH versus acute anterior uveitis associated with ankylosing spondylitis

BACKGROUND: It has been reported that the gut microbiome is involved in the pathogenesis of uveitis, but the specific pathogenic microbes and metabolites in different types of uveitis are still unclear.

METHODS:&...

2023-12-12 | MTBLS7936 | MetaboLights
TranscriptomicsTranscription profiling of human macrophages from ankylosing spondylitis patients reveals interferon-gamma dysregulation
OBJECTIVE: To determine whether macrophages, a type of cell implicated in the pathogenesis of ankylosing spondylitis (AS), exhibit a characteristic gene expression pattern. METHODS: Macrophages were derived from the peripheral blood of 8 AS patients (median disease duration 13 years [range <1-43 yea...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11886 | biostudies-arrayexpress
TranscriptomicsAnkylosing spondylitis vs control synovial biopsies
We have compared synovial biopsies from ankylosing spondylitis and undifferentiated spondylitis patients with healthy controls and osteoarthritis patients Objective: In spondylarthropies, whole-genome gene expression profiling studies have been limited to peripheral blood to date. By undertaking a...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-41038 | biostudies-arrayexpress
TranscriptomicsSingle cell RNAseq of ankylosing spondylitis lymphocytes from peripheral blood and synovial fluid
Single-cell transcriptome of >55,000 cells multiplexed into 4 channels obtained from peripheral blood and synovial fluid of two patients with HLA-B27+ ankylosing spondylitis,.
ORGANISM(S): Homo sapiens 
2021-10-18 | E-MTAB-10948 | biostudies-arrayexpress
ProteomicsColon Mucosal Proteomics of Ankylosing Spondylitis versus Chronic Enteritis
To identify differentially expressed proteins (DEPs) in colon tissue of patients with ankylosing spondylitis (AS) versus patients with chronic enteritis using proteomic techniques, and to investigate the functions of the DEPs and the relationship between AS and chronic enteritis.
ORGANISM(S): Homo sapiens (Human) 
2024-12-03 | PXD032159 | Pride
Ankylosing spondylitis  chronic enteritis  proteomics  colon mucosa nmral1 
GenomicsGenomewide association studies in ankylosing spondylitis
The aim of this study was to identify genes associated with ankylosing spondylitis susceptibility in British and Australian individuals of European descent.
EGAS00000000104 | EGA
GenomicsWTCCC2 Ankylosing spondylitis cases - individual
WTCCC1 project Ankylosing Spondylitis (AS) samples
EGAD00000000010 | EGA
ProteomicsProteomic characterization of peripheral blood mononuclear cells from ankylosing spondylitis patients
Ankylosing spondylitis (AS) is an inflammatory arthritis of the axial skeleton that predominantly affects young men. HLA-B27 has remained the major genetic risk factor in AS. Recently, more non-MHC genes has been discoverd to be involved in AS pathogenesis, especially IL-23 signalling pathway relate...
ORGANISM(S): Homo sapiens (Human) 
2023-04-15 | PXD024989 | Pride
Pbmc Proteomics Ankylosing spondylitis 
GenomicsWTCCC case-control study for Ankylosing Spondylitis
WTCCC genome-wide case-control association study for Ankylosing Spondylitis (AS) using the 1958 British Birth Cohort collection as controls.
EGAS00000000018 | EGA
GenomicsWTCCC case-control study for Ankylosing Spondylitis - Combined Controls
WTCCC genome-wide case-control association study for Ankylosing Spondylitis (AS) - Combined Controls.
EGAS00000000019 | EGA
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