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ProteomicsLFQ comparison of total cell lysate, lysosomal and plasma membrane fraction of WT and NPC1 KO cells
Superparamagnetic iron oxide nanoparticles (SPIONs) have so far mainly been used as cellular carriers for genes and therapeutic products, while their use in subcellular organelle isolation remains largely underexploited. We engineered surface functionalized SPIONs (Ø 10 nm) that target very distinc...
ORGANISM(S): Homo sapiens (Human) 
2017-02-01 | PXD004273 | Pride
Lysosomal fraction Niemann-pick disease type c1 Label-free quantification Superparamegnetic iron oxide nanoparticles 
ProteomicsLFQ comparison of total cell lysate, lysosomal and plasma membrane fraction of WT and NPC1 KO cells
Superparamagnetic iron oxide nanoparticles (SPIONs) have so far mainly been used as cellular carriers for genes and therapeutic products, while their use in subcellular organelle isolation remains largely underexploited. We engineered surface functionalized SPIONs (Ø 10 nm) that target very distinc...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080792 | MassIVE
ProteomicsNovel surface functionalized superparamagnetic nanoparticles with engineered cellular uptake as a means for intracellular omics
Superparamagnetic nanoparticles (SPMNPs) are appealing for use in organelle isolation strategies. Yet, this potential remains largely unexplored because thus far research has focused on either physicochemical design or on their application in micron-sized beads. For their use in life sciences, the b...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080688 | MassIVE
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