Sort   by:  
 Page size 
GenomicsANP32B-deficiency suppresses ocular development by repression of PAX6
ANP32B-deficiency suppresses ocular development by repression of PAX6
PRJNA1120104 | ENA
TranscriptomicsANP32B-deficiency suppresses ocular development by repression of PAX6
We observed that the deletion of Anp32b led to severe defects in ocular development, such as anophthalmia and microphthalmia. Moreover, Anp32b was highly expressed in the lens, and Anp32b−/− embryos with microphthalmia typically exhibited severely impaired lens development. Mechanistically, ANP32B d...
ORGANISM(S): Mus musculus 
2025-06-02 | GSE269101 | GEO
GenomicsANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells
ANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells
PRJNA764729 | ENA
GenomicsANP32B suppresses B-cell acute lymphoblastic leukemia development through activation of PU.1 in mice
ANP32B suppresses B-cell acute lymphoblastic leukemia development through activation of PU.1 in mice
PRJNA884349 | ENA
UnknownANP32B is a nuclear target of henipavirus M proteins.
Not available
S-EPMC4019565 | biostudies-literature
TranscriptomicsANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells
we demonstrate that conditional deletion of acidic leucine-rich nuclear phosphoprotein 32B (ANP32B) in hematopoietic cells impairs repopulation capacity and postinjury regeneration of HSCs. Mechanistically, ANP32B forms a repressive complex with and thus inhibits the transcriptional activity of p53 ...
ORGANISM(S): Homo sapiens Mus musculus 
2021-09-27 | GSE184474 | GEO
TranscriptomicsANP32B suppresses B-cell acute lymphoblastic leukemia development through activation of PU.1 in mice
The acidic leucine-rich nuclear phosphoprotein 32B (ANP32B) is critical for maintenance of normal and leukemia stem cells. However, no data exist on ANP32B requirement in B-cell acute lymphoblastic leukemia (B-ALL) progression. Here, we observe that ANP32B is lowly expressed in B-ALL patients, which...
ORGANISM(S): Mus musculus 
2025-09-24 | GSE214199 | GEO
UnknownANP32B deficiency impairs proliferation and suppresses tumor progression by regulating AKT phosphorylation.
Not available
S-EPMC4849165 | biostudies-literature
GenomicsCUT-TAG for AML cell lines with either no treatment or ANP32B knockdown
CUT-TAG for AML cell lines with either no treatment or ANP32B knockdown
PRJNA1013815 | ENA
GenomicsANP32B promotes colorectal cancer cell progression and reduces cell sensitivity to PRAP1 inhibitor through up-regulating HPF1
ANP32B promotes colorectal cancer cell progression and reduces cell sensitivity to PRAP1 inhibitor through up-regulating HPF1
PRJNA1036664 | ENA
Sort   by:  
 Page size