Anti-tumor antibody

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Unknown (6119)
Transcriptomics (4193)
Genomics (1058)
Proteomics (184)
Clinical (40)
Other (25)
Metabolomics (14)
Genomic (2)
Models (1)
Methylation profiling (1)

Organisms

Homo sapiens (1990)
Mus musculus (1380)
Rattus norvegicus (124)
Arabidopsis thaliana (89)
Drosophila melanogaster (67)
Saccharomyces cerevisiae (57)
Bos taurus (45)
Gallus gallus (41)
Sus scrofa (38)
Danio rerio (37)
Caenorhabditis elegans (26)
Zea mays (18)
Oryza sativa (18)
Canis lupus familiaris (17)
Streptococcus pneumoniae D39 (16)
Ovis aries (16)
Escherichia coli (13)
Macaca mulatta (13)
Oryza sativa Japonica Group (12)
Schizosaccharomyces pombe (10)
Oncorhynchus mykiss (9)
Medicago truncatula (8)
Salmo salar (8)
Staphylococcus aureus (7)
Carassius auratus (6)
Glycine max (6)
Colinus virginianus (5)
Equus caballus (5)
Bacillus subtilis (5)
Solanum lycopersicum (5)

Organisms

Mus musculus (394)
Homo sapiens (343)
Rattus norvegicus (3)
Macaca mulatta (2)
Homo sapiens/Mus musculus xenograft (1)
Euarchontoglires (1)
unidentified (1)
Mus (1)
Mammalia (1)
Mus (1)
Canis lupus familiaris (1)
Mus musculus musculus (1)
Arabidopsis thaliana (1)

Repository

biostudies-arrayexpress (3944)
ENA (852)
geo (478)
pride (87)
EGA (62)
iProX (14)
MetaboLights (14)
MassIVE (13)
jPOST (6)
dbGaP (2)
EVA (2)
NODE (2)
ExpressionAtlas (1)
BioModels (1)

Tissue

Cell culture (22)
Epithelial cell (10)
B cell (5)
Skin (5)
Blood (4)
Dendritic cell (4)
Liver (4)
Lung (4)
Permanent cell line cell (4)
T cell (4)
Cell suspension culture (3)
Colon (3)
Kidney (3)
Melanocyte (3)
Ovary (3)
Pancreas (3)
Spleen (3)
Tumor graft (2)
Blood cell (2)
Blood plasma (2)
Brain (2)
Breast (2)
Hepatocyte (2)
Monocyte (2)
Pancreatic adenocarcinoma cell line (2)
Peripheral blood mononuclear cell (2)
Ascites (1)
Astrocyte (1)
Bile duct (1)
Blood serum (1)

Disease

Normal (7)
Breast cancer (7)
Glioblastoma (3)
Testicular seminoma (1)
CLL (1)
Arrhythmias and right ventricular dysfunction (1)
GIP-dependent Cushing's syndrome (1)
HPV positive (1)
Osteosarcoma subtype fibroblastic (1)
High grade glioblastoma (1)
Cocaine addiction (1)
Primary effusion lymphoma (PEL) (1)
DNA damage (1)
Dermal neurofibroma (1)
Breast Carcinoma (1)
Uninfected (1)
Myasthenia gravis (seropositive patient with low thymic hyperplasia) (1)
Renal cancer (1)
Schizophrenia (1)
Colon Cancer (1)
Epidermoid carcinoma (1)
Primary tumor (1)
Leukemia (1)
Locally advanced rectal cancer (1)
Renal cell carcinoma (1)
Prostate carcinoma (1)
Adenocarcinoma (1)
Nodal peripheral T-cell Lymphoma (1)
Collagen induced arthritis (1)
Multiple myeloma (1)

Technology Type

Mass Spectrometry (87)
Shotgun proteomics (39)
Data-dependent acquisition (21)
Affinity purification coupled with mass spectrometry proteomics (17)
Bottom-up proteomics (14)
Mass spectrometry assay (9)
Gel-based experiment (8)
Mass spectrometry (5)
Data-independent acquisition (4)
Immunopeptidomics (3)
Top-down proteomics (3)
SWATH MS (2)
NextSeq 500, Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2000, Illumina Genome Analyzer IIx (1)
Illumina HiSeq 2000 (1)
Illumina MiSeq (1)
NMR spectroscopy assay (1)
Affinity proteomics (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
DiaPASEF (1)
Glycoproteomics (1)
Mass spectrometry imaging (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (43)
Illumina HiSeq 2000 (21)
Illumina HiSeq 2500 (19)
Illumina HiSeq 4000 (17)
Illumina HiSeq 1500 (10)
NextSeq 500 (10)
Illumina NovaSeq X (4)
NextSeq 2000 (3)
Illumina MiSeq (3)
NextSeq 550 (3)
BAS-5000 [FUJIFILM] (2)
Illumina Genome Analyzer IIx (2)
Illumina Genome Analyzer II (2)
NA (2)
Illumina HiSeq 2000 platform (1)
Digital Alliance of Canada (1)
AAV-CRISPR (1)
10X Dual Index Kit (1)
10X Chromium Next GEM Single-Cell 3' Kit v3.1 (1)
Using NEBNext Ultra II DNA Library (1)
10X Genomics Single Cell, V3.1 (1)
NCounter Pro and nCounter Pro Analysis System (1)
Qubit 4.0 and TapeStation (1)
Element AVITI (1)
Agilent 2100 Bioanalyzer, Applied Biosystems 7900HT Sequence Detection System, Illumina TruSeq Small RNA Sample Preparation Kit (1)
RNeasy mini Kit, Ribo-Zero Human/Mouse/Rat kit (1)
GenePix 4000 (1)
Solexa 2G Genome Analyzer (1)
BD FACSAria III (1)
Not applicable (1)

Publication Date

2015 (648)
2010 (592)
2013 (586)
2014 (448)
2012 (420)
2011 (416)
2008 (197)
2016 (191)
2009 (163)
2026 (131)
2025 (116)
2021 (94)
2007 (87)
2023 (85)
2022 (85)
2024 (83)
2020 (47)
2019 (47)
2018 (35)
2006 (27)
2017 (25)
2005 (19)
2004 (10)
2003 (6)
2002 (2)

UNIPROT ID/AC

P05231 (1)
P08887 (1)

CHEBI ID

CHEBI:17295 (2)
CHEBI:60050 (1)
CHEBI:84520 (1)
CHEBI:15801 (1)
CHEBI:1156 (1)
CHEBI:133617 (1)
CHEBI:30660 (1)
CHEBI:176760 (1)
CHEBI:58115 (1)
CHEBI:28832 (1)
CHEBI:34498 (1)
CHEBI:18258 (1)
CHEBI:17566 (1)
CHEBI:71169 (1)
CHEBI:23965 (1)
CHEBI:16990 (1)
CHEBI:30865 (1)
CHEBI:18211 (1)
CHEBI:16828 (1)
CHEBI:17053 (1)
CHEBI:16958 (1)
CHEBI:16856 (1)
CHEBI:35697 (1)
CHEBI:17895 (1)
CHEBI:18050 (1)
CHEBI:16865 (1)
CHEBI:18261 (1)
CHEBI:17033 (1)
CHEBI:16946 (1)
CHEBI:18307 (1)

Metabolite Name

L-Phenylalanine (3)
L-Tryptophan (2)
L-Tyrosine (2)
L-Glutamine (2)
Dihydrooroticacid (1)
Fumaricacid (1)
Guanosine5'-monophosphate (1)
[(9S)-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-h]chromen-9-yl] (Z)-2-methylbut-2-enoate (1)
[(3S,6S)-6-[5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)chromenylium-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate (1)
[(2R)-3-Hexadecoxy-2-hydroperoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate (1)
Val-Thr-Ala-Asp-Lys (1)
Val-Leu-Ser-Asp (1)
Val-Glu-Thr-Glu (1)
Val-Asn-Tyr-Val-Asn (1)
Val-Arg-His-Arg (1)
Tyr-Trp-Phe (1)
Tyr-His-Leu (1)
Tyr-Arg-Ile-Glu (1)
Tubocurarine chloride (1)
Trp-Pro-Leu (1)
Trp-Phe-Glu (1)
Trp-Glu-Asp (1)
Thr-Val-Ile-Thr-Gly (1)
Thr-Thr-Asp-Glu-Tyr (1)
Thr-Asp-Phe-Glu (1)
Ser-Glu-Val-Lys-Met (1)
Ser-Glu-Lys-Ile-Asp (1)
Ser-Arg-Lys-Glu-Ser (1)
S-Isopropyl-isothiourea (1)
PtdIns-(4)-P1 (1,2-dihexanoyl) (1)

First Public Date

2025 (168)
2026 (138)
2024 (111)
2023 (100)
2021 (83)
2022 (63)
2014 (53)
2019 (34)
2020 (32)
2018 (29)
2017 (15)
2015 (15)
2016 (9)
2013 (2)

Modelling Approach

Ordinary differential equation model (1)

Study status

Completed (13)
Recruiting (9)
Not provided (8)
Terminated (3)
Active, not recruiting (3)
Withdrawn (2)
Not yet recruiting (2)

Lab affiliation

Institute for Research in Immunology and Cancer, Department of Biochemistry, Department of Chemistry, Université de Montréal, Québec, Canada H3T 1J4 (3)
OncoProteomics Laboratory, Dept of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands (3)
Department of Pathology and Cell Biology and Institute for Cancer Genetics Herbert Irving Comprehensive Cancer Vagelos College of Physicians & Surgeons Columbia University (2)
Immunology Unit, Department of Cell Biology, Physiology and Immunology, Institut de Biotecnologia i Biomedicina (IBB), Universitat Autònoma de Barcelona (UAB), Bellaterra (Cerdanyola del Vallès), Spain Biosensing and Bioanalysis Group, Institut de Biotecnologia i Biomedicina (IBB), Universitat Autònoma de Barcelona (UAB), Bellaterra (Cerdanyola del Vallès), Spain (2)
Prof. Dr. M. Waheed Akhtar, School of Biological Sciences, University of the Punjab, Lahore, Pakistan (2)
1 Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands 2 Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Associate Professor, Department of Pathology, Faculty of Medicine, The University of Hong Kong (1)
BriaCell Therapeutics Corporation, Berkeley, CA, USA (1)
CRG, UPF (1)
Calico Life Sciences (1)
Cancer Proteomics Lab Department of Molecular Cell Biology Weizmann Institute of Science, Rehovot (1)
Centre de recherche du Centre Hospitalier Universitaire (CHU) de Quebec-Université Laval, Québec, QC, Canada Centre de recherche sur le cancer de l’Université Laval, Québec, QC, Canada PROTEO-Quebec Network for Research on Protein Function, Engineering, and Applications, Québec, QC, Canada Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Québec, QC, Canada (1)
Chan Zuckerberg Biohub, Stanford, CA, USA (1)
Charité-University Medicine Berlin (1)
Clinical Collaboration Unit Translational Immunology, German Cancer Consortium (DKTK), Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany (1)
Columbia University Department of Biological Sciences and Department of Chemistry (1)
Department of Biochemistry and Molecular Biology Hollings Cancer Center Medical University of South Carolina, 86 Jonathan Lucas Street, Charleston, SC 29425; (1)
Department of Biological Engineering, MIT (1)
Department of Chemistry, National and Kapodistrian University of Athens, 15784 Zografou, Greece (1)
Department of Chemistry, Southern University of Science and Technology, Shenzhen, China (1)
Department of Chemistry, University of Oslo, Oslo, Norway (1)
Department of Immunology, Weizmann Institute of Science (1)
Department of Integrated Immunobiology Duke School of Medicine Durham, NC, USA (1)
Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, MN 55905 USA (1)
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota (1)
Department of Medical BioSciences, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, The Netherlands (1)
Department of Medicine, Columbia University (1)
Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada (1)
Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Canada (1)

Keyword

Bevacizumab (9)
Antibodies (8)
Antibodies, Monoclonal (5)
Fluorouracil (5)
Irinotecan (4)
Leucovorin (4)
Oxaliplatin (4)
Bispecific antibody (3)
Nivolumab (3)
Capecitabine (3)
Levoleucovorin (3)
Cetuximab (3)
Antibody (2)
EGFR (2)
MCRC (2)
Durvalumab (2)
Pembrolizumab (2)
Panitumumab (2)
Antineoplastic Agents, Immunological (2)
Immunoglobulins (2)
Chemotherapy (2)
Calcium (2)
Gastric (gastroesophageal cancer) (1)
CD39 (1)
Adenosine Pathway (1)
Immunotherapy Immuno-oncology (1)
Budigalimab (1)
TTX-030 (1)
Urothelial cell cancer (1)
PD-1 Checkpoint Inhibitor (1)

IsPrivate

False (1)

Submitter Keywords

Immuno-oncology (1)

Study type

Transcription profiling by array (2733)
RNA-seq of coding RNA (450)
Unknown experiment type (123)
ChIP-seq (101)
RNA-seq of non coding RNA (91)
ChIP-chip by tiling array (52)
Proteomic profiling by array (52)
Comparative genomic hybridization by array (50)
Other (49)
Methylation profiling by array (48)
RNA-seq of coding RNA from single cells (38)
Transcription profiling by SAGE (33)
Transcription profiling by tiling array (18)
Transcription profiling by RT-PCR (17)
ChIP-chip by array (15)
Methylation profiling by high throughput sequencing (10)
Cell line - High-throughput sequencing (9)
Genotyping by array (8)
Human - High-throughput sequencing (6)
DNA-seq (4)
Cell line - One-color microarray (3)
MicroRNA profiling by high throughput sequencing (3)
High-throughput sequencing (2)
Animal - High-throughput sequencing (2)
RNAi profiling by array (2)
Antigen profiling (2)
MicroRNA profiling by array (2)
RNA-seq of total RNA (2)
ChIP-chip by SNP array (1)
Transcription profiling by MPSS (1)

Release Date

2015 (881)
2022 (782)
2013 (694)
2023 (674)
2021 (670)
2010 (648)
2014 (614)
2025 (605)
2024 (575)
2020 (559)
2012 (506)
2011 (484)
2016 (454)
2019 (448)
2018 (369)
2017 (346)
2008 (229)
2009 (215)
2007 (109)
2026 (100)
2006 (34)
2005 (26)
2004 (16)
2003 (7)
2002 (6)
1998 (5)
2000 (3)
2001 (2)
1999 (2)

Location

United States (15)
China (11)
France (7)
Italy (4)
Spain (4)
Germany (3)
Belgium (3)
Netherlands (3)
United Kingdom (3)
South Korea (2)
Taiwan (1)
Denmark (1)
Portugal (1)
Poland (1)
Czechia (1)
Switzerland (1)
Sweden (1)

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Transcription profiling by array of human SK-N-AS neuroblastoma xenograft tumor treated with anti-human IGF-IR monoclonal antibody (h10H5) to study the anti-tumour function of the antibody

The insulin-like growth factor (IGF) system consists of two ligands (IGF-I and IGF-II), which both signal through type I IGF receptor (IGF-IR) to stimulate proliferation and inhibit apoptosis, with activity contributing to malignant growth of many types of human cancers. We have developed a humanize...

ORGANISM(S): Homo sapiens

2008-10-25 | E-GEOD-11959 | biostudies-arrayexpress

Systemically administered extremely low HMGN1 with anti-CD4 depleting antibody exerts synergistic anti-tumor effects

PRJNA450754 | ENA

RNA profiling of PB-020 and anti-PD-1 antibody treated MC38 tumor tissue

PRJNA783079 | ENA

Immune-stimulating antibody conjugates elicit robust myeloid activation and durable anti-tumor immunity II

PRJNA663155 | ENA

TNF blockade uncouples toxicity and anti-tumor efficacy induced with an agonist CD40 antibody

PRJNA656939 | ENA

SILAC-based quantitative proteomics of cancer cells treated with the anti-tumor antibody 14F7

An investigation of the effect of humanized 14F7 on HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC) in combination with LC-MS and microscopy.

ORGANISM(S): Homo sapiens (Human)

2022-08-08 | PXD024320 | Pride