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To elucidate the function of oxidative phosphorylation (OxPhos) during B-cell differentiation we employ CD23Cre-driven expression of the dominant-negative K320E mutant of the mitochondrial helicase Twinkle (DNT). DNT-expression depletes mitochondrial DNA during B cell maturation, reduces the abun...

2026-08-21 | MTBLS4647 | MetaboLights
PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity
Autophagy Suppresses CD8+ T cell Anti-tumour Immunity
Modelling of anti-tumour immune response: Immunocorrective effect of weak centimetre electromagnetic waves O.G. Isaeva* and V.A. Osipov Bogoliubov Laboratory of Theoretical Physics, Joint Institute for Nuclear Research, Dubna, Moscow Region, Russia We formulate the dynamical model for the anti-tumo...
2024-09-02 | BIOMD0000000910 | BioModels
Interleukin-4 modulates type I interferon to augment anti-tumour immunity
PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity
The stress response regulator HSF1 modulates natural killer cell anti-tumour immunity
Interleukin-4 modulates type I interferon to augment anti-tumour immunity [scRNA-Seq]
The PTPN2/N1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity [TIL_RNAseq]
The PTPN2/N1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity [TIL_ATACseq]
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